PREPARE: A Pragmatic Randomized trial Evaluating Pre-operative Alcohol skin solutions in FRactured Extremities
R
Roman Natoli, MD
Primary Investigator
Overview
The overarching objective of this trial is to compare the effectiveness of iodine povacrylex (0.7% free iodine) in 74% isopropyl alcohol versus 2% chlorhexidine gluconate (CHG) in 70% isopropyl alcohol for the management of extremity fractures that require surgical treatment.
Description
After participants agree to take part in this study, researchers will collect data on demographics, fracture characteristics, pre-operative data, and peri-operative data.
Researchers will then collect reoperation and SAE data at routine clinic visits 6 weeks, 3 months, 6 months, 9 months, and 12 months later.
Eligibility
You may be eligible for this study if you meet the following criteria:
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Conditions:
bone fracture, orthopedic surgery
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Age: Between 18 Years - 100 Years
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Gender: All
Individuals at least 18 years of age with an open fracture, with open fracture wound management that includes definitive fracture treatment with surgical debridement within 72 hours of injury.
Individuals with chronic or acute infection or burns at the fracture site will not be eligible.
Updated on
25 Apr 2024.
Study ID: ORTHO-MARYLAND-PREPARE, 1904652838
