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Found 736 All Conditions trials

A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Fracture-Related Outcome Study for Operatively Treated Tibia Shaft Fractures (FROST)

R
Roman Natoli, MD
18 years and older
All genders
Observational
Approximately 1000 patients presenting with tibial shaft fractures (AO type 42) will bed prospectively in this registry. All patients are treated and followed at 6 weeks, 6hs and 1 year postoperative always following the local standard of care (routine) visithedule up to 36 months if required. Data collection includes patient …
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Mismatched Related Donor Versus Matched Unrelated Donor Stem Cell Transplantation for Children, Adolescents, and Young Adults With Acute Leukemia or Myelodysplastic Syndrome

T
Toshihiro Onishi, MD
6-21 years
All genders
Phase 3
Interventional
This phase III trial compares hematopoietic (stem) cell transplantation (HCT) usinghed related donors (haploidentical [haplo]) versus matched unrelated donors (MUD) ing children, adolescents, and young adults with acute leukemia or myelodysplasticyndrome (MDS). HCT is considered standard of care treatment for patients with high-riskute leukemia and MDS. In HCT, patients are …
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Personalized Perioperative Analgesia Platform (PPAP) for Pediatric Spine Fusion Surgery (sIRB) (PPAP Spine)

S
Senthil Packiasabapathy
10-17 years
All genders
Interventional
The purpose of this collaborative CTSA application is to develop an innovative perioperativegesia platform (PPAP) to improve analgesia and reduce serious immediate andg-term adverse outcomes of perioperative opioids in children undergoing painful surgery.
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Clinical, Imaging, and Endoscopic Outcomes of Children Newly Diagnosed With Crohn's Disease (CAMEO)

M
Marian Pfefferkorn
6-17 years
All genders
Observational
Crohn's disease (CD) is a condition that causes inflammation (swelling, redness) of theg and wall of the small intestine, large intestine, or both. CD may be associated withbdominal cramps/pain, diarrhea, blood in the stool, weight loss, or delayed growth inhildren. While the exact cause of CD is not certain it …
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Pelvic Health Electrically Evoked Recording (PEER) 2 Study (PEER 2)

C
Charles Powell, MD
18 years and older
All genders
Interventional
To collect physiological signals at several timepoints during the therapy evaluation period.
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Patient Satisfaction of Virtual vs In-Person Workup and Treatment of Lower Urinary Tract Symptoms.

M
Marcelino Rivera
18 years and older
Healthy Volunteer
All genders
This study is being done to compare usefulness of data collected in uroflowmetry, a test thatures the amount of urine released from the body, at home versus in the doctor's office. Additionally, investigators are assessing patient satisfaction when completing a virtual visit for lower urinary tract symptoms (LUTS), related to …
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ONC201 in H3 K27M-mutant Diffuse Glioma Following Radiotherapy (the ACTION Study) (ACTION)

All genders
Phase 3
Interventional
This is a randomized, double-blind, placebo-controlled, parallel-group, international, Phase 3 study in patients with newly diagnosed H3 K27M-mutant diffuse glioma to assess whetherwith ONC201 following frontline radiotherapy will extend overall survival andgression-free survival in this population. Eligible participants will have histologically diagnosed H3 K27M-mutant diffuse glioma and have completed standard …
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A Study of Combination Therapy With Guselkumab and Golimumab in Participants With Moderately to Severely Active Ulcerative Colitis (DUET-UC)

S
Sashidhar Sagi, MD
18-65 years
All genders
Phase 2
Interventional
The purpose of this study is to evaluate the efficacy and safety of JNJ-78934804 as comparedguselkumab and golimumab in participants with moderately to severely active ulcerativewho have had an inadequate initial response, loss of response, or intolerance to oneved advanced therapy.
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Phase 2b Study of GSK4532990 in Adults With NASH (HORIZON)

N
Niharika Samala, MD
18-75 years
All genders
Phase 2
Interventional
The purpose of this study is to measure improvements in liver fibrosis and inflammation with GSK4532990 compared with placebo in participants with NASH and advanced (F3) fibrosis. Theudy duration will be up to 76 weeks including the screening period. The treatment duration will be up to 52 weeks.
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Biologic Abatement and Capturing Kids' Outcomes and Flare Frequency in Juvenile Spondyloarthritis (BACK-OFF JSpA)

S
Stacey Tarvin, MD
8-21 years
All genders
Interventional
This randomized pragmatic trial will generate knowledge about strategies used to de-escalateumor necrosis factor inhibitor (TNFi) therapy in patients with juvenile spondyloarthritis with sustained inactive disease and are treated at one of the 29 participating pediatric healthcare systems. This open label study will be conducted in the setting of routined …
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