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Found 594 results for iu-health-enterprise-system

A listing of iu-health-enterprise-system medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

An Open-Label, Multicenter, Outpatient Extension Study to Evaluate the Safety and Tolerability of Staccato Alprazolam in Study Participants 12 Years of Age and Older With Stereotypical Prolonged Seizures

M
Marlene Bultemeher
12 years - 17 years
All genders
Interventional
The purpose of the study is to evaluate the long-term safety and tolerability of Staccato alprazolam.THIS STUDY IS ENROLLING BY INVITATION ONLY

Genetic Determinants of Persistent Lactic Acidosis in Major Burn Patients: A Whole-Genome Sequencing Approach

F
Faith Zor
18 years - 100 years
All genders
Observational
The purpose of this study is to find out whether certain genetic differences may explain why some severely burned patients continue to have high lactic acid levels in their blood even after receiving proper medical treatment. We will collect a small blood sample from each patient and analyze their DNA …

A Phase 3, Randomized, Double-Blind Study to Evaluate the Efficacy and Safety of Veverimer in Adults with Ckd and Metabolic Acidosis (REVIVE)

K
Kenneth Lim
18 years - 100 years
All genders
Phase 3
Interventional
The purpose of this 26 week study is is to evaluate the efficacy and safety of veverimer in treating adults with moderate-to-severe chronic kidney disease (CKD) and metabolic acidosis.THIS STUDY IS ENROLLING BY INVITATION ONLY

Evolve: Evaluation of the Fully Closed Loop Omnipod System for Safety and Efficacy in Adults With Type 2 Diabetes

V
Viral Shah
18 years - 75 years
All genders
Interventional
A multi-center, 26-week randomized controlled trial (RCT) to evaluate the safety and efficacy of the fully closed loop Omnipod M System in adults with type 2 diabetes using basal/bolus insulin therapy or basal-only insulin therapy, with the primary endpoint after 15 weeks and secondary analysis at 26 weeks; followed by …

Oral Responses Associated with Colostrum Exposure in Neonates (ORACLE-Neo) - An Observational Study of NICU Oral Care Practices and Mucosal Immune Markers

K
Kok Lim Kua
All genders
Observational
The goal of this study is to evaluate current oral care practices in the NICU (completed with oral swab with either mother's breast milk or sterile water) and correlate with infant outcomes primarily related to immune responses with secondary investigation into neonatal rates of infection, growth parameters and length of …

Serum Endothelin-1 Levels in Pediatric Patients After Cardiac Transplantation

M
Michael Johansen, DO
All genders
Observational
The purpose of this study is to find out more about a substance in the blood, called Endothelin-1, or ET-1, after a child has a heart transplant.

EVOLVE Trial - EndoVascular Treatment Of Wide-Neck Aneurysms

B
Bradley N. Bohnstedt, MD
18 years - 80 years
All genders
Interventional
The purpose of this study is to collect data on the use of the Surpass Evolve Flow Diverter to determine its safety and efficacy.

HEALEY ALS Platform: Multi-Center, Multi-Regimen clinical trial evaluating investigational products for the treatment of ALS

C
Cynthia Bodkin, MD
18 years - 100 years
All genders
Interventional
ALS is a degenerative disorder of the nerves controlling movement (“motor neurons”). ALS causes muscles to become weak, which leads to paralysis. ALS is a condition that gradually damages the nerve cells in the brain and spinal cord.  Currently, there are no treatments to prevent, reverse, or stop the development of …

Selatogrel Outcome Study in Suspected Acute Myocardial Infarction (SOS-AMI)

M
Mohammed Madmani, MD
R
Rolf Kreutz, MD
All genders
Phase 3
Interventional
This study will randomize patients recently discharged from the hospital with a confirmed diagnosis of type 1 acute myocardial infarction (Thygesen et al. 2018) and having additionaldiovascular risk factors.

Longitudinal Study of Genetic Causes of Intrahepatic Cholestasis (LOGIC) (LOGIC)

J
Jean Molleston, MD
All genders
Observational
Cholestasis is a condition in which bile is not properly transported from the liver to the. Cholestasis can be caused by an array of childhood diseases, including the genetic diseases Alagille syndrome (ALGS), alpha-1 antitrypsin (a-1AT) deficiency, bile acidynthesis and metabolism defects, and progressive familial intrahepatic cholestasis (PFIC) or benign …
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