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Found 6 sarah-pardue-brennan trials

A listing of sarah-pardue-brennan medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Testing the Addition of Chemotherapy Drug, Cisplatin, to Usual Radiation Therapy for Patients with Head and Neck Cancer

G
Greg Durm, MD
18 years - 100 years
All genders
Phase 2
Interventional
The purpose of this study is to compare two treatment approaches that are currently used after surgery for head and neck cancer. One approach is to administer radiation therapy alone. A second approach is to administer radiation therapy along with the chemotherapy drug, cisplatin.
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A Randomized, Double-Blind, Placebo-Controlled Phase 3b Study to Evaluate the Short- and Long-Term Efficacy and Safety of Dual Targeted Therapy With Intravenous Vedolizumab and Oral Upadacitinib Compared With Intravenous Vedolizumab Monotherapy for the Treatment of Adult Participants With Moderately to Severely Active Crohn's Disease

M
Monika Fischer, MD
18 years - 65 years
All genders
Phase 3
Interventional
What is the purpose of this study?The main aim of this study is to learn whether vedolizumab and upadacitinib given together (also called dual targeted therapy or DTT) reduces bowel inflammation and ulcers in the bowel compared to vedolizumab only (also called monotherapy) in adults with moderately or severely active …
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Standardized Microbiota Transplant Therapy in Crohn's Disease - Pilot Trial

M
Monika Fischer, MD
18 years - 100 years
All genders
Phase 2
Interventional
Crohn's disease (CD) develops because of a disruption of homeostasis between the gut microbiota and the host immune system resulting in excessive inflammation in the intestinal tract. Current drug therapies for CD are directed at the immune system. The emergence of fecal microbiota transplantation (FMT) for the treatment of recurrent …
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Fecal Microbiota Transplant (FMT) National Registry

M
Monika Fischer, MD
100 years or below
All genders
What is the purpose of this study?This is a national data registry of patients receiving fecal microbiota transplantation (FMT) or other gut-related-microbiota products designed to prospectively assess short and long-term safety and effectiveness. This registry will prospectively enroll 4,000 patients who undergo FMT at 75 sites throughout North America. This …
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Research Study on Targeted Therapies for Moderate to Severe Crohn's Disease

M
Monika Fischer, MD
18 years - 75 years
All genders
Phase 2
Interventional
This study investigates targeted therapies for adults with moderate to severe Crohn's disease. Crohn's disease is a long-lasting condition that causes inflammation in the digestive tract, often affecting the bowels. Symptoms can include belly pain, diarrhea, tiredness, and weight loss. The study aims to evaluate the effectiveness and possible side …
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A Phase 3, Randomized, Double-Blind, Placebo-Controlled Program toEvaluate the Efficacy and Safety of Tulisokibart in Participants with Moderately to SeverelyActive Crohn's Disease

M
Monika Fischer, MD
16 years - 75 years
All genders
Phase 3
Interventional
What is the purpose of this study?The purpose of this protocol is to evaluate the efficacy and safety of tulisokibart in participants with moderately to severely active Crohn's disease. The protocol consists of 2 studies. Study 1 includes induction and maintenance treatment, and Study 2 includes only induction treatment. Each study …
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