A listing of site-public-contact medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
This study investigates the safety of using chemoradiation instead of surgery for early stage vulvar cancer. Vulvar cancer is a type of cancer that affects the external female genitalia. In some cases, cancer spreads to nearby lymph nodes. This study looks at patients with a macrometastasis, which means the cancer …
This phase III trial compares the effect of sentinel lymph node mapping to standard lymph node dissection in reducing the risk of swelling in the legs (lymphedema) in patients undergoing a hysterectomy for stage I endometrial cancer. Standard lymph node dissection removes lymph nodes around the uterus during a hysterectomy …
What is the purpose of this study?The goal of this clinical study is to find out how the study drug, sacituzumab govitecan (SG) works in participants with endometrial cancer who have received prior treatment with platinum-based chemotherapy and immunotherapy, versus the treatment of physician's choice (TPC).Interested in participating? For more …
What is the purpose of this study?People with Oropharyngeal squamous cell carcinoma (OPSCC) typically receive standard treatment with a combination of chemotherapy, radiation therapy, and surgery. Due to the intensity of standard treatment, survivors may experience unwanted long-term side effects. The goal of this research study is to see if …
What is this study about?This phase II/III trial examines whether patients who have undergone surgical removal of bladder, but require an additional treatment called immunotherapy to help prevent their bladder cancer from coming back, can be identified by a blood test. Many types of tumors tend to lose cells or …
This study investigates the connection between stress, race, and breast cancer. Breast cancer is a disease where cells in the breast grow uncontrollably. The study looks at how stress and racial differences may affect breast cancer types and outcomes.Participants will be part of two groups: one to develop a stress …
This study investigates the use of MRI surveillance alone versus MRI surveillance combined with prophylactic cranial irradiation (PCI) in patients with small cell lung cancer. Small cell lung cancer is a type of cancer that forms in the tissues of the lung and can spread quickly. MRI, or magnetic resonance …
What is the purpose of this study?This is a multicenter, randomized, open label phase lll trial to assess whether preoperative chemotherapy, as an adjunct to curative-intent surgery, improves the prognosis of high risk DDLPS (dedifferentiated Liposarcoma) and LMS (Leiomyosarcoma) patients as measured by disease free survival. Interested in participating? For more …
This study investigates the effects of adding an investigational medication, cemiplimab, to the usual treatment of docetaxel and ramucirumab for patients with stage IV or recurrent non-small cell lung cancer. This type of lung cancer is advanced and may have returned after previous treatment. Cemiplimab is a monoclonal antibody that …
What is the purpose of this study?This phase III trial compares the effect of stereotactic radiosurgery to standard of care memantine and whole brain radiation therapy that avoids the hippocampus (the memory zone of the brain) for the treatment of small cell lung cancer that has spread to the brain. …