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Found 21 results for Alzheimer's Disease
A listing of Alzheimer's Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
Dominantly Inherited Alzheimer Network (DIAN)
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Martin Farlow, MD
Dominantly inherited Alzheimer's disease (AD) represents less than 1% of all cases of AD and is an important model for study because the responsible mutations have known biochemical consequences that are believed to underlie the pathological basis of the disorder. The overall purpose of this research is to understand the …
Enhancing shared decision-making to prompt and guide individualized care for people with Alzheimer's Disease and Diabetes
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April Savoy
For patients and caregivers, ADRD-DM presents unique challenges for detecting and preventing hypoglycemia.Individualized care for people with ADRD-DM should be based on patient and caregiver goals along with patients’ cognitive and physical abilities, reported outcomes, and hypoglycemia risk, based largely on prior hypoglycemic events. Providing details of hypoglycemic events and risks …
The Assessment of Smart Phone Everyday Tasks (ASSET): A new IADL test for early AD
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Liana Apostolova, MD
What is the purpose of this study?The overall goal of this project is to validate a novel performance-based IADL instrument that uses a smartphone to assess healthcare-related daily activities, ASSET. This IADL test has been designed to tap the high-level tasks that challenge seniors in daily life, to serve as …
Validation of Video Administration of a Modified UDSv3 Cognitive Battery
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Andrew Saykin, PsyD
The purpose of this research is to determine whether common tests of memory and thinking can be administered by video on a computer or tablet, and if these tests are useful when administered this way as compared to being given in person.
Reducing Risk of Dementia through Deprescribing: Cognitive Outcomes After AntiCholinergic Reduction (R2D2: COACH)
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Malaz Boustani, MD
A cluster-randomized controlled trial (RCT) called "Reducing Risk of Dementia through Deprescribing" (R2D2) to evaluate the impact of a deprescribing intervention on important cognitive and safety outcomes. This study will evaluate the effects of the use of a program to reduce prescribing of a group of commonly prescribed medications called …
The ADRC Consortium for Clarity in ADRD Research Through Imaging (CLARITI)
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Shannon Risacher
This study seeks to identify the several possible causes of dementia that may be present in an individual, and that may be contributing to a person’s current or future cognitive symptoms. The study will run a panel of experimental and established biomarker tests for the several causes of dementia such …
Determinants of Incident Stroke Cognitive Outcomes and Vascular Effects on RecoverY (DISCOVERY)
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Jason Mackey
The overall goal of the DISCOVERY study is to better understand what factors contribute tohanges in cognitive (i.e., thinking and memory) abilities in patients who experienced ake. The purpose of the study is to help doctors identify patients at risk for dementia (decline in memory, thinking and other mental abilities …
Multi-Modal Large Language Model-Empowered Talk Therapy for Older Adults with ADRD
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Malaz Boustani, MD
The purpose of this study is to test the usefulness and the effect of the Smart Virtual Reminiscence (SVR) therapy intervention on the Behavioral and Psychological Symptoms of Dementia (BPSD) of patients with Alzheimer’s Disease and Related Dementias (ADRD). BPSD refers to changes in behavior and mood that often occur in dementia, …
ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD)
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David Clark
ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD) represents thezed integration of ARTFL (U54 NS092089; funded through 2019) and LEFFTDS (U01 AG045390; funded through 2019) as a single North American research consortium to study FTLD2019 and beyond.
Comparison of Two Group Wellness Interventions for Individuals with Neurologic Conditions and Their Support Persons: A Randomized Clinical Trial
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Devan Parrott
The goal of this study is to examine efficacy of the treatment in individuals with chronic mild TBI and their caregivers and to determine whether patient neurobehavioral functioning moderates the relationship between treatment outcomes and burden in caregivers. Beyond injury-based cohorts, we sought to examine whether WeCAN would be efficacious …
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