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Found 19 orthopedics trials

A listing of orthopedics medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Long-FRI

R
Roman Natoli, MD
18 years - 85 years
All genders
The overall aim of this proposal is to identify a biomarker diagnostic strategy that can be implemented in patients sustaining fractures at high-risk for infection. This proposal will address the hypothesis that there is a biomarker signature that will be able to discriminate between patients who develop FRI compared to …
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Healthy Volunteers Needed For Ankle Fracture and Pain Study!

F
Fletcher White
K
Kelly Naugle
R
Roman Natoli, MD
18 years - 85 years
Accepts healthy volunteer
All genders
What is this study about?The purpose of this study is to teach us more about why some people often experience persistent pain after having a bone fracture. We want to determine whether certain factors place individuals more at risk for experiencing persistent pain after a bone fracture including pain sensitivity …
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Utility of Serum Biomarkers in Diagnosing Fracture-Related Infections: A Pilot Study

R
Roman Natoli, MD
18 years - 85 years
Accepts healthy volunteer
All genders
The primary aim will be to determine if serum inflammatory biomarkers can reliably diagnose FRIs as compared to a standardized definition of FRI.
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IS PATIENT KNOWLEDGE AND EXPECTATIONS FOR OUTPATIENT SHOULDER ARTHROPLASTY CONCORDANT WITH THEIR SURGICAL EXPERIENCE?

M
Mark Dillon
18 years - 100 years
All genders
Observational
What is this study about?The purpose of the proposed study is to evaluate whether patient knowledge and expectations for outpatient primary total shoulder arthroplasty (replacement, TSA), defined as discharge to home from the post-acute care unit by midnight on the day of surgery, are concordant with their surgical experiences.  THIS STUDY …
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Antibacterial Drape Study in Surgery

L
Leonard Buller
22 years - 100 years
All genders
Interventional
This study investigates the use of an antibacterial drape in orthopedic surgeries, specifically hip or knee replacements. The purpose is to see how well the drape works in preventing contamination during surgery. An incise drape is a type of covering used during surgery to keep the area clean and prevent …
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Investigating Muscle Changes in Trauma Patients Using Special Images Taken of the Body

T
Todd McKinley, MD
18 years - 55 years
All genders
This study investigates muscle changes in people who have had a traumatic injury. The purpose is to see if muscle deterioration affects recovery. Muscle deterioration means losing muscle mass, which can happen after a serious injury. The study looks at CT scans, which are special images taken of the body, …
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The Effect of Lower Extremity Fracture Non-union on Gait

Y
Yohan Jang
18 years - 85 years
All genders
Observational
What is the purpose of this study?This study aims to understand how lower leg fractures that don’t heal properly affect walking speed. It also seeks to verify if the Apple iPhone can accurately measure walking speed and other gait characteristics in people with these injuries.THIS STUDY IS ENROLLING BY INVITATION …
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Effect of NSAIDs on Union, Opioid Utilization and Pain Management for Tibia Fractures

K
Karl Shively
B
Brian Mullis, MD
18 years - 80 years
All genders
Phase 3
Interventional
The proposed study is a two arm, pragmatic, randomized controlled multicenter Phase IIIy trial. 1,000 patients with tibia fractures treated with intramedullary (IM)will be randomized into two treatment arms. The control arm will receive standard paingement and no NSAIDs. The treatment arm will receive standard pain management plus up toweeks …
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Studying Genes in Muscle Pressure Condition

D
Dillon O'Neill
18 years - 100 years
All genders
Observational
The purpose of this study is to investigate the genetic differences and local gene expression in people who develop acute traumatic compartment syndrome. Compartment syndrome is a serious condition where increased pressure within a muscle compartment reduces blood flow, affecting tissue health. This study compares individuals with compartment syndrome to …
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A Randomized Controlled Trial Comparing Antibiotic Cement Bead Pouch Versus Negative Pressure Wound Therapy for the Management of Severe Open Tibia Fracture Wounds

Y
Yohan Jang
18 years - 100 years
All genders
Interventional
What is this study about?Open tibia fracture complications are debilitating for patients. NPWT is the current standard of care for temporary wound management of severe open fractures requiring multiple debridements. Emerging comparative studies suggest that the antibiotic bead pouch may significantly reduce the risk of open fracture infection and its …
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