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Found 28 Orthopedics trials

A listing of Orthopedics medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Intraarticular distal femur extreme nailing results

W
Walter Virkus, MD
100 or below
All genders
The purpose of this study is to determine the outcomes of retrograde IMN and ORIF in the treatment of intraarticular distal femur fractures.
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REPAIR: Rehabilitation Enhanced by Partial Arterial Inflow Restriction - a METRC (Major Extremity Trauma Research Consortium) Study

T
Todd McKinley, MD
100 or below
All genders
The purpose of this study is to test the effectiveness of the REPAIR intervention when compared to usual care PT alone.
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Treatment of Tibial Pilon and Plateau Fractures with Intramedullary Nailing- Evaluation of Outcome

A
Anthony Sorkin, MD
100 or below
All genders
The purpose of this study is to compare clinical outcomes of patients that underwent IMN for tibial plateau fractures to patients that underwent ORIF for similar fractures; and to compare clinical outcomes of patients that underwent IMN for tibial pilon fractures to patients that underwent ORIF for similar fractures.
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Serum Protein-Based Indices for the Progression of Fracture Healing and Nonunion

R
Roman Natoli, MD
18 - 70
All genders
To define a serum protein-based diagnostic for the progression and failure of fracture healing, through the identification of a set of serum proteins that appear at early times of biological healing and show a specific correlation with later radiological and functional signs used to define delayed healing and non-union. 
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Early Serial Sampling of Peripheral Blood for the Purposes of Predicting Fracture Nonunion

R
Roman Natoli, MD
18 - 60
All genders
The purpose of this study is to determine if certain molecules in the bloodstream can be used to improve our ability to predict the development of a nonunion or unhealed bone or fracture related infection.  This study is looking at many molecules and we will determine if the levels of …
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Intranasal Povidone Iodine (PVI) to Prevent Staphylococcus aureus

T
Todd McKinley, MD
18 - 100
All genders
Phase 4
The purpose of this research study is to find out if applying iodine to the inside of the nose prevents Staph infections among patients having operations to fix broken bones.
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COgnitive and Physical Exercise to Improve Outcomes After Surgery (COPE-iOS) Study (COPEiOS)

R
Roman Natoli, MD
60 or above
All genders
Interventional
The COgnitive and Physical Exercise to improve Outcomes after Surgery (COPE-iOS) study isg the hypothesis that a pragmatic program combining computerized cognitive training andhysical training throughout the perioperative period will improve long-term cognitive and disability outcomes in older surgical patients at high risk for decline. To accomplish these goals, the …
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Cast or Operation for Medial Epicondyle Fracture Treatment in Children (COMET)

E
Erika Daley
7 - 17
All genders
Interventional
This protocol describes a multicenter, prospective randomized superiority trial of medialdyle fracture treatments comparing functional outcomes between children treated withve reduction and fixation or non-operative immobilization.
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Effect of NSAIDs on Union, Opioid Utilization and Pain Management for Tibia Fractures

K
Karl Shively
B
Brian Mullis, MD
18 - 80
All genders
Phase 3
Interventional
The proposed study is a two arm, pragmatic, randomized controlled multicenter Phase IIIy trial. 1,000 patients with tibia fractures treated with intramedullary (IM)will be randomized into two treatment arms. The control arm will receive standard paingement and no NSAIDs. The treatment arm will receive standard pain management plus up toweeks …
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Precision Medicine Approach Based on Discrete Time Windows for Predicting Outcomes of Polytrauma Patients (Windows)

T
Todd McKinley, MD
18 - 55
All genders
Observational
The goal of this project is to obtain blood samples and test to see how each individual’s body is responding to traumatic injuries in order to better understand how to treat patients with injuries like these in the future.
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