A listing of Breast Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
This study investigates treatments for people with HER2-positive breast cancer. HER2-positive means that the cancer cells have more HER2 protein than normal, which can cause cancer cells to grow. The study looks at using a combination of investigational medication injections and hormone therapy after surgery. The investigational medications are trastuzumab …
This study investigates treatments for patients with residual triple negative breast cancer, a type of breast cancer that does not have estrogen, progesterone, or HER2 receptors. The study uses circulating tumor DNA (ctDNA) to assign participants to different treatment arms based on their genomic markers. Participants with ctDNA positivity and …
This study investigates the effects of an investigational medication alone compared to the same medication combined with tocilizumab in patients with advanced breast cancer. Advanced breast cancer includes conditions such as metastatic triple negative or ER-low breast cancer. This study involves Black and non-Black patients and aims to understand how …
This study investigates the treatment of breast cancer in patients who have hormone-sensitive, HER-2 negative tumors with a low recurrence score. The purpose is to understand if breast conservation surgery with only endocrine therapy is as effective as combining it with radiation therapy in preventing the return of cancer in …
What is the purpose of this study?This Phase III, randomized, open-label, multicenter study will evaluate the efficacy andy of giredestrant plus everolimus compared with the physician's choice of endocrineherapy plus everolimus in participants with estrogen receptor (ER)-positive, human epidermal growth factor receptor 2 (HER2)-negative locally advanced or metastatic breast cancer …
What is the purpose of this study?This trial studies how well 68-Ga RM2 works with PET/MRI in imaging patients with estrogen receptor-positive breast cancer. 68-Ga-RM2 is an agent used in diagnostic imaging.Primary: To describe the safety of 68Ga-R10602.Secondary - To describe the biodistribution of 68Ga-R10602 in Study Participants with hormone …
This study investigates whether adding chemotherapy to ovarian function suppression and hormone therapy improves breast cancer-free survival in premenopausal women. The focus is on those with early-stage breast cancer that is estrogen receptor-positive and HER2-negative. The study will compare outcomes between those receiving chemotherapy in addition to hormone treatments and …
Why is this study being done?The purpose of this study is to test a program for Black women and their families at risk of breast cancer to have access to community health advocates that will help them understand their risk of developing breast cancer, navigate screenings, and access additional ways …
This study investigates why women with metastatic breast cancer choose not to participate in exercise programs designed for their needs. Metastatic breast cancer is when cancer has spread beyond the breast to other parts of the body. Understanding the reasons for non-participation can help improve future program designs.Participants will complete …
This study investigates how genetic ancestry affects the completion of treatment in patients diagnosed with breast cancer. Breast cancer is a disease where cells in the breast grow out of control. This study involves newly diagnosed women with stages I-III breast cancer who self-report as Black or White.Participants will provide …
