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Found 25 Lung Disease trials

A listing of Lung Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

G
Greg Durm, MD
18 years - 100 years
All genders
Phase 2
Interventional
What is the purpose of this study?This phase II trial studies the effects of temozolomide and atezolizumab as second or thirdwith small cell lung cancer that has spread to other places inhe body (metastatic) or has come back (recurrent). Chemotherapy drugs, such as temozolomide, work in different ways to stop …
N
Nasser Hanna, MD
18 years - 100 years
All genders
Phase 2
Interventional
This study investigates the use of circulating tumor DNA (ctDNA) to personalize treatment for patients with stage III non-small cell lung cancer (NSCLC). The purpose is to use ctDNA analysis to guide therapy decisions, instead of relying solely on clinical or radiographic evidence of disease. This approach aims to tailor …
G
Greg Durm, MD
18 years or above
All genders
Phase 3
Interventional
What is the purpose of this study?The main objective is to compare the efficacy of tarlatamab with standard of care (SOC) on prolonging overall survival (OS).THIS STUDY IS ENROLLING BY INVITATION ONLY - Consistent with most oncology trials, patients are not actively “recruited,” but are screened by their physician for …
R
Rohan Maniar
18 years or above
All genders
Phase 1/2
Interventional
What is the purpose of this study?Part 1: A first-in-human, open-label, Phase I dose escalation study of DSP107 monotherapy and combination therapy with atezolizumab in patients with advanced solid tumors. Part 2: Preliminary efficacy assessment of DSP107 in combination with atezolizumab in second or third line treatment of non small …
R
Ryan Boente
18 years - 100 years
All genders
1. To assess the feasibility and utility of a remote monitoring platform for rural ILD patients. 2. To assess adherence and attitudes of rural patients to home spirometry requiring a web application. 3. To determine time spent reviewing the data portal by the medical team.  
S
Shadia Jalal, MD
18 years - 100 years
All genders
What is the purpose of this study?This is pilot study to establish a rapid autopsy program in Small Cell Lung Cancer (SCLC) at the Indiana University Simon Comprehensive Cancer Center and outline the components necessary for tumor tissue collection. This proposal is a collaboration between scientists, lung cancer physicians, pathologists, …
R
Ryan Boente
C
Chadi Hage, MD
18 years - 100 years
All genders
The purpose of this study is to find new ways to detect, treat, and maybe prevent or cure lung diseases.
C
Catherine Sears, MD
18 years or above
All genders
This study investigates how airway and blood cells from adult patients repair DNA after exposure to airborne pollutants, such as tobacco smoke. The purpose is to understand the effects of these pollutants on DNA repair mechanisms in different cell types. We will collect cells from the airways and blood of …
O
Onyedika Ilonze
18 years - 100 years
All genders
Interventional
This study investigates the use of an ECG-based artificial intelligence (AI) device to assess the risk of undiagnosed pulmonary hypertension (PH) in patients with interstitial lung disease (ILD). The purpose of this study is to determine if the device can increase the rate of new PH diagnoses compared to the …
M
Marc Rovner
18 years - 100 years
All genders
Phase 3
Interventional
This study investigates the effects of an investigational medication on people with moderate to very severe Chronic Obstructive Pulmonary Disease (COPD). COPD is a long-term lung disease that makes it hard to breathe. The purpose of this study is to see how well the investigational medication works compared to a …
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