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Found 21 Lung Disease trials

A listing of Lung Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

A Phase II Study of Amivantamab SC (subcutaneous) in Participants with MET Amplification-Positive Stage IV or Recurrent Non-Small Cell Lung Cancer (Lung-MAP Sub-Study)

R
Rohan Maniar
18 years - 100 years
All genders
Phase 2
What is the purpose of this study?This phase II Expanded Lung-MAP treatment trial tests how well amivantamab-subcutaneous (SC) works in treating patients patients with MET amplification non-small cell lung cancer. Amivantamab-SC is a drug that reduces extra copies of the MET gene, a change present in your tumor. Giving amivantamab-SC …
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Investigation of Blood Samples from Stage IV Non-Small Cell Lung Cancer Patients

V
Vijay Khatri
100 years or below
All genders
This study investigates the collection of fresh blood from patients with Stage IV Non-Small Cell Lung Cancer (NSCLC). NSCLC is a type of lung cancer that is characterized by the uncontrolled growth of cells in the lung tissue. Stage IV indicates that the cancer has spread beyond the lungs to …
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A Phase 2 Study of EIK1001 in Combination with Pembrolizumab and Chemotherapy in Patients with Stage 4 Non-Small Cell Lung Cancer

R
Rohan Maniar
18 years - 100 years
All genders
Phase 2
What is the purpose of this study?This is a multicenter open-label phase 2 trial that aim to assess the safety, tolerability, and efficacy of EIK1001 in combination with standard of care in participants with both confirmed stage 4 squamous and non-squamous NSCLC who have not received prior systemic therapy for …
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Phase III Trial of Stereotactic Radiosurgery (SRS) versus Hippocampal-Avoidant Whole Brain Radiotherapy (HA-WBRT) for Brain Metastases from Small Cell Lung Cancer.

K
Kevin Shiue
18 years - 100 years
All genders
Phase 3
What is the purpose of this study?This phase III trial compares the effect of stereotactic radiosurgery to standard of care memantine and whole brain radiation therapy that avoids the hippocampus (the memory zone of the brain) for the treatment of small cell lung cancer that has spread to the brain. …
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Investigation of Treatment Combinations for Advanced Non-Small Cell Lung Cancer

R
Rohan Maniar
18 years - 100 years
All genders
Phase 2/3
This study investigates the effects of adding an investigational medication, cemiplimab, to the usual treatment of docetaxel and ramucirumab for patients with stage IV or recurrent non-small cell lung cancer. This type of lung cancer is advanced and may have returned after previous treatment. Cemiplimab is a monoclonal antibody that …
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Research on Medicine for Pancreatic and Lung Cancer

A
Anita Turk, MD
18 years - 100 years
All genders
This study investigates the safety and effects of an investigational medication in combination with other agents for patients with pancreatic or non-small cell lung cancer. These cancers are being studied because they have specific genetic changes called MTAP loss and RAS mutation. The purpose is to see how the investigational …
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Stigma in Lung Cancer and Tobacco-Related Cancers

B
Bharathi Muthusamy
18 years - 100 years
All genders
This study investigates the stigma experienced by patients with lung cancer and other tobacco-related cancers, such as pancreatic adenocarcinoma, renal cell carcinoma, and urothelial carcinoma. A stigma is a mark of disgrace associated with a particular condition. The purpose of this study is to understand how stigma affects patients with …
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Study on Support for Cancer Patients

A
Alexia Torke
18 years - 100 years
All genders
This study investigates the impact of informational support versus spiritual care on patients with cancer. Cancer patients often face challenges in coping with their condition and making treatment decisions. Religion and spirituality can play significant roles in their experience. Therefore, this study will evaluate a spiritual care intervention delivered by …
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Thoracotomy Versus Thoracoscopic Management of Pulmonary Metastases in Patients With Osteosarcoma

S
Sandeep Batra, MD
1 year - 50 years
All genders
Phase 3
Interventional
What is the purpose of this study?This phase III trial compares the effect of open thoracic surgery (thoracotomy) tohoracoscopic surgery (video-assisted thoracoscopic surgery or VATS) in treating patients with osteosarcoma that has spread to the lung (pulmonary metastases). Open thoracic surgeryype of surgery done through a single larger incision (like …
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Study of Investigational Medication for KRAS Mutant Solid Tumors

G
Greg Durm, MD
18 years - 100 years
All genders
Phase 1/2
This study investigates an investigational medication for people with solid tumors that have specific KRAS mutations. These mutations are changes in a gene that can affect how cells grow. The purpose of this study is to understand if the investigational medication is safe and can be tolerated by patients with …
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