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Found 26 Orthopedic Surgery trials

A listing of Orthopedic Surgery medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Assessment of barriers to clubfoot treatment in the state of Indiana

R
Robert Bielski
100 years and younger
All genders
Investigate the various barriers that affect adherence to the Ponseti method for clubfoot treatment in the state of IndianaTo assess the impact of these barriers on the rate of missed or discontinued clinic visits within the first three months of treatment
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Long-FRI

R
Roman Natoli, MD
18-85 years
All genders
The overall aim of this proposal is to identify a biomarker diagnostic strategy that can be implemented in patients sustaining fractures at high-risk for infection. This proposal will address the hypothesis that there is a biomarker signature that will be able to discriminate between patients who develop FRI compared to …
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Utility of Serum Biomarkers in Diagnosing Fracture-Related Infections: A Pilot Study

R
Roman Natoli, MD
18-85 years
Accepts healthy volunteer
All genders
The primary aim will be to determine if serum inflammatory biomarkers can reliably diagnose FRIs as compared to a standardized definition of FRI.
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Effects of Skeletal Trauma on the Metabolome

T
Todd McKinley, MD
T
Todd Owen Mckinley
18-55 years
All genders
Observational
The purpose of this study is to assess the effects of skeletal trauma on the human metabolome, or the pathways by which the body creates, stores, and breaks down energy.
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What is the role of Next Generation Sequencing (NGS) in nonunion of orthopaedic cases?

R
Roman Natoli, MD
18-100 years
All genders
The purpose of this study is to investigate the role of Next Generation Sequencing (NGS), a molecular method to detect bacterial DNA presence, in 1) diagnosis of infected nonunion compared to microbiological culture and 2) compare NGS signal with clinical outcome and fracture healing.
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Risks of Anemia versus Transfusion in Orthopedic Trauma Patients

B
Brian Mullis, MD
18-50 years
All genders
The purpose of this study is to determine if there is a difference in outcomes between liberal transfusion and conservative transfusion.
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Long Term Consequences of Major Extremity Trauma

T
Todd McKinley, MD
18-100 years
All genders
This research is being done to collect data about the long term physical and psychosocial effects of orthopaedic trauma. This study will try out methods of collecting data, including questionnaires and clinic exams, in order to inform how larger studies collecting similar long-term effects should be done.
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CT-Based Muscle Changes in a Retrospective Cohort of Patients

T
Todd McKinley, MD
18-55 years
All genders
The purpose of this study is that patients who have muscle deterioration after experiencing a traumatic injury will have worse long term outcomes than patients who do not have muscle deterioration.
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Intraarticular distal femur extreme nailing results

W
Walter Virkus, MD
100 years and younger
All genders
The purpose of this study is to determine the outcomes of retrograde IMN and ORIF in the treatment of intraarticular distal femur fractures.
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REPAIR: Rehabilitation Enhanced by Partial Arterial Inflow Restriction - a METRC (Major Extremity Trauma Research Consortium) Study

T
Todd McKinley, MD
100 years and younger
All genders
The purpose of this study is to test the effectiveness of the REPAIR intervention when compared to usual care PT alone.
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