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Found 151 Neoplasms trials

A listing of Neoplasms medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

 Survivors of colon and rectal cancer, your community needs YOUR voice! Join our study to empower yourself while helping others.
D
David Haggstrom, MD
18 years or above
All genders
Interventional
DO YOU WANT TO HELP FELLOW SURVIVORS OF COLON AND RECTAL CANCER? Join the Survivorship Plan HEalth REcord (SPHERE) study to help us deliver survivorship care tools and resources designed for people like you!  We are looking for volunteers, 18 years of age or older, who have recently undergone surgery for …
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Online study
B
Brian Weiss
12 months or above
All genders
Phase 1/2
Interventional
What is the purpose of this study?This phase I/II trial studies how well tiragolumab and atezolizumab works when given tohildren and adults with SMARCB1 or SMARCA4 deficient tumors that that has either come back (relapsed) or does not respond to therapy (refractory). SMARCB1 or SMARCA4 deficiency meanshat tumor cells are …
R
Rohan Maniar
18 years or above
All genders
Phase 1/2
Interventional
What is the purpose of this study?Part 1: A first-in-human, open-label, Phase I dose escalation study of DSP107 monotherapy and combination therapy with atezolizumab in patients with advanced solid tumors. Part 2: Preliminary efficacy assessment of DSP107 in combination with atezolizumab in second or third line treatment of non small …
M
Mateusz Opyrchal, MD, PhD
18 years - 100 years
All genders
Phase 1
Interventional
What is the purpose of this study?This is a first-in-human, Phase I, open-label, multicenter study designed to evaluate they, tolerability and preliminary efficacy of WTX-124, a conditionally-activated IL-2drug, when administered as monotherapy and in combination with pembrolizumab, for thewith advanced solid tumors. THIS STUDY IS ENROLLING BY INVITATION ONLY - …
N
Nabil Adra, MD
18 years or above
All genders
Phase 2
Interventional
What is the purpose of this study?This is an open label randomized phase II trial of maintenance oral etoposide vs. observationwith relapsed GCT treated with high-dose chemotherapy (HDCT) and peripheral-blood(PBSCT).THIS STUDY IS ENROLLING BY INVITATION ONLY - Consistent with most oncology trials, patients are not actively “recruited,” but are screened …
B
Brian Weiss
1 years - 21 years
All genders
Interventional
What is the purpose of this study?This phase I/II trial evaluates the best dose, side effects and possible benefit of CBL0137 in treating patients with solid tumors, including central nervous system (CNS) tumors or lymphoma that has come back (relapsed) or does not respond to treatment (refractory). Drugs, such as …
M
Marissa Just
30 years or below
All genders
Phase 2
Interventional
What is the purpose of this study?This phase II trial studies how well combination chemotherapy works in treating patients withwly diagnosed stage II-IV diffuse anaplastic Wilms tumors (DAWT) or favorable histology Wilms tumors (FHWT) that have come back (relapsed). Drugs used in chemotherapy regimens suchH-3 (vincristine, doxorubicin, cyclophosphamide, carboplatin, etoposide, …
B
Brian Weiss
12 months - 30 years
All genders
Phase 1/2
Interventional
What is the purpose of this study?This phase I/II trial evaluates the highest safe dose, side effects, and possible benefits ofgavivint in treating patients with solid tumors that has come back (recurrent) or does notd to treatment (refractory). Tegavivint interferes with the binding of beta-catenin to TBL1, which may help …
L
Lisa Landrum, MD, PhD, MS
18 years or above
All genders
Phase 3
Interventional
What is the purpose of this study?GLORIOSA is a Phase 3 multicenter, open label study designed to evaluate the safety and efficacy of mirvetuximab Soravtansine as maintenance therapy in participants with platinum-sensitive ovarian, primary peritoneal or fallopian tube cancers with high folate receptor-alpha (FRα) expression.THIS STUDY IS ENROLLING BY INVITATION …
L
Lisa Landrum, MD, PhD, MS
18 years or above
Female
Phase 3
Interventional
What is the purpose of this study?This is a Phase 3, multicenter, open-label, randomized study of nemvaleukin in combination with pembrolizumab versus protocol-specific Investigator's choice chemotherapy in patients with platinum-resistant epithelial ovarian, fallopian tube, or primary peritoneal cancer.THIS STUDY IS ENROLLING BY INVITATION ONLY - Consistent with most oncology trials, …
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