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Found 17 Solid Tumor trials

A listing of Solid Tumor medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

M
Mateusz Opyrchal, MD, PhD
18 years - 100 years
All genders
Phase 1/2
What is the purpose of this study?Phase 1a Dose Escalation/Cohort Expansion BBO-10203 Monotherapy Primary: To evaluate the safety and tolerability of BBO-10203, an inhibitor of the PI3Kα:RAS interaction, in subjects with locally advanced unresectable or metastatic (ie, advanced) HER2-positive BC; HR-positive, HER2-negative BC; KRAS mutant NSCLC; and KRAS mutant CRC. Secondary: To evaluate …
M
Mateusz Opyrchal, MD, PhD
18 years - 100 years
All genders
This study investigates an investigational medicine for treating adults with advanced cancers that have high levels of a protein called fibroblast activation protein (FAP). The purpose of this study is to evaluate safety, side effects, and the amount of the investigational medicine that enters the bloodstream, how it is broken …
G
Greg Durm, MD
18 years - 100 years
All genders
Phase 1
This study investigates the safety and effects of an investigational antibody-drug conjugate in patients with advanced or metastatic solid tumors. The purpose is to understand how the investigational medication works in the body and its impact on tumors. Advanced or metastatic solid tumors are cancers that have spread beyond their …
J
James Croop, MD, PhD
1 years - 21 years
All genders
This study is designed to investigate whether the use of copanlisib is safe, feasible and beneficial to pediatric patients with solid solid tumors or lymphoma that are recurrent or refractory to standard therapy.
M
Mateusz Opyrchal, MD, PhD
18 years - 100 years
All genders
Phase 1/2
This study investigates the safety and effects of an investigational medication in people with advanced solid tumors. Advanced solid tumors are cancers that have spread and do not respond well to regular treatments. The purpose of this study is to find out how safe the medication is, how the body …
B
Brian Weiss
12 months - 21 years
All genders
Phase 1/2
Interventional
This study investigates the use of an investigational medication in patients with relapsed or refractory solid tumors, including central nervous system tumors and lymphoma. The purpose is to find the best dose and understand the side effects and potential benefits. Solid tumors and lymphoma are types of cancer that can …
A
April Rahrig, MD
2 years - 18 years
All genders
Phase 3
This study investigates the use of an investigational medication to prevent cytomegalovirus (CMV) infection in children and adolescents who have undergone a stem cell transplant. Cytomegalovirus is a virus that can cause infections, especially in people with weakened immune systems. "Prophylaxis" means taking a drug to prevent a disease or …
S
Sandeep Batra, MD
15 years - 20 years
All genders
This study investigates a home-based physical activity program designed for Hispanic or Latino/Latina adolescent and young adult (AYA) childhood cancer survivors. After cancer treatment, some AYA survivors may experience long-term effects like weight gain, tiredness, and reduced fitness. Hispanic or Latino/Latina survivors might face a higher risk of these effects. …
T
Tarah Ballinger, MD
40 years or below
Female
Phase 3
This study investigates the effects of an investigational medication on protecting the ovaries in young females with cancer who are receiving chemotherapy. Chemotherapy, particularly with alkylating agents, can harm the ovaries, making it hard to get pregnant later. The investigational medication may help by slowing down the ovaries during chemotherapy, …
C
Cindy Yuan
18 years - 100 years
All genders
Phase 1
This study investigates the use of an investigational imaging substance in people with advanced solid tumors. The purpose is to understand how safe this substance is and how well it works in taking pictures of tumors inside the body. It will compare these pictures to the ones taken with regular …
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