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Found 4 Down's Syndrome trials

A listing of Down's Syndrome medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Development of trial-ready cohort to facilitate rapid enrollment into Alzheimer’s trials for participants with Down Syndrome (Trial Ready Cohort—Down Syndrome (TRC-DS)

J
Jill Fodstad
35 years - 55 years
All genders
Interventional
Who is Eligible Ages 35-55 Must be willing to complete PET scan What is Involved Onsite visits at the IUH Neuroscience Center Visits at the IUH Neuroscience Center every 16 months Compensation Compensation available via payment card for each completed appointment
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A phase 1b/2, multicenter, adaptive, double-blind, randomized, placebo-controlled study to assess the safety, tolerability, immunogenicity, and pharmacodynamic effects of ACI-24.060 in subjects with prodromal Alzheimer's disease and in adults with Down syndrome (ABATE)

J
Jill Fodstad
35 years - 50 years
All genders
Phase 1/2
Interventional
What is this study about?The purpose of this study is to assess the safety, tolerability, immunogenicity and pharmacodynamic effects of ACI-24.060 in subjects with prodromal Alzheimer's disease and in non-demented adults with Down syndrome.This phase 1b/2 study will be in 2 parts. Study Part 1 will involve subjects with prodromal …
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Study of Treatments for Relapsed B-Cell Acute Lymphoblastic Leukemia

S
Sandeep Batra, MD
1 year - 30 years
All genders
Phase 2
Interventional
This study investigates the effects of two investigational medications, blinatumomab and nivolumab, in patients with B-cell acute lymphoblastic leukemia (B-ALL) that has relapsed. B-ALL is a type of cancer that affects the white blood cells. The study includes patients with Down syndrome and aims to compare the outcomes of using …
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Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS) (POPS or POP02)

G
Gregory Sokol, MD
20 years or below
Accepts healthy volunteer
All genders
The study investigators are interested in learning more about how drugs, that are given tohildren by their health care provider, act in the bodies of children and young adults in hopes to find the most safe and effective dose for children. The primary objective of thisudy is to evaluate the …
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