Found 12 results for Cystic Fibrosis
A listing of Cystic Fibrosis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
Cystic Fibrosis CFTR Modulator Study
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Emma Tillman
We hope to generate data through the variability in medication concentrations in a persons blood. We do not know yet if drug concentrations correlate with side effects. This study will help determine if CFTR modulator blood concentrations correlate with medication side effects and determine the value of proceeding with a …
VOLUNTEERS NEEDED: Asthma, COPD, CF, or Healthy! Support LUNG HEALTH by being AWARE!
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Erick Forno
Are you interested in TECHNOLOGY? Join our AWARE (Acoustic Waveform Respiratory Evaluation) Research Study! Why is this study being done?Researchers at the Indiana University School of Medicine are doing a research study to understand how well smartphone technology can measure the size of your airways and if it can help diagnose …
Standardizing Treatments for Pulmonary Exacerbations - Aminoglycoside Study (STOP360AG)
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Cynthia Brown, MD
The purpose of this study is to look at pulmonary exacerbations in people with cysticbrosis (CF) that need to be treated with antibiotics given through a tube inserted into a vein (intravenous or IV). A pulmonary exacerbation is a worsening of respiratory symptoms inwith CF that needs medical intervention. Both …
Breath-based Diagnosis of Pulmonary Exacerbations in Children with Cystic Fibrosis
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Mangilal Agarwal
What is the purpose of this study?The purpose of this study is to obtain and measure compounds found in exhaled breath samples collected from children with Cystic Fibrosis (CF). These compounds should be different when CF patients are healthy compared to when they have an exacerbation. This information could help …
Prevalence and Longitudinal Course of Depression, Anxiety, and Behavior Problems in Children with Cystic Fibrosis Under 12 Years of Age
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Emma Tillman
This is a longitudinal, observational epidemiological study designed to estimate the prevalence of depression, anxiety, and behavior problems in children ages 18 months through 11 years with cystic fibrosis (CF). THIS STUDY IS ENROLLING BY INVITATION ONLY
A Research Study to Advance the CF Therapeutics Pipeline for People Without Modulators
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Don Sanders, MD
What is the purpose of this study?The REACH study is for people with CF who do not take cystic fibrosis transmembrane conductance regulator (CFTR) modulators. The goal of the REACH study is to collect research data, including health data and specimens, from people with CF who do not take CFTR …
Streamlined Treatment of Pulmonary Exacerbations in Pediatrics Randomized Controlled Trial
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Don Sanders, MD
The STOP PEDS RCT is a multicenter, parallel, open label randomized controlled trial evaluating the long-term (one year) and short-term safety and efficacy of two antibiotic treatment strategies for the management of outpatient pulmonary exacerbations (PEx) in the pediatric CF population.THIS STUDY IS ENROLLING BY INVITATION ONLY
Sinonasal Therapies and Histologic Correlations for Patients with Cystic Fibrosis in the Era of Highly Effective Modulator therapy
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Elisa Illing
Establish a protocol for de-escalation of sinonasal therapies for patients on cystic fibrosis transmembrane regulator (CFTR) modulator therapies in a multidisciplinary fashion that includes a Rhinology perspective. Test the hypothesis that patients with cystic fibrosis on CFTR modulator therapy with refractory sinus disease exhibit continued tissue neutrophilic inflammation. THIS STUDY IS …
Restarting Triple Therapy With Robust Monitoring for Adverse Events (RETRIAL)
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Emma Tillman
RETRIAL is a prospective, longitudinal, observational, multi-site study designed to observe what happens when people with Cystic Fibrosis (PWCF) with a history new/worsening mental health symptoms or liver toxicity while taking elexacaftor/tezacaftor/ivacaftor (ETI), start taking vanzacaftor/tezacaftor/deutivacaftor (VTD).THIS STUDY IS ENROLLING BY INVITATION ONLY - Eligible PWCF will be identified by …
The CHEC-SC Cohort Study: CHaractErizing CFTR Modulated Changes in Sweat Chloride and their Association with Clinical Outcomes (the CHEC-SC study)
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Don Sanders, MD
This is a multicenter, cross-sectional, cohort study which will collect contemporary sweat chloride (SC) values from approximately 5000 Cystic Fibrosis (CF) patients prescribed and currently receiving commercially approved Cystic Fibrosis transmembrane conductance regulator (CFTR) modulator therapies. THIS STUDY IS ENROLLING BY INVITATION ONLY
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