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Found 16 results for Diabetes Mellitus, Type 1

A listing of Diabetes Mellitus, Type 1 medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Denosumab for Type 1 Diabetes

C
Carmella Evans-Molina, MD
18 years - 50 years
All genders
Phase 1/2
Interventional
Researchers at City of Hope (California), University of Alabama at Birmingham, and Indiana University are studying a medication called denosumab as a potential treatment for people with type 1 diabetes. Denosumab, also known as Prolia, is a drug that has been approved by the Food and Drug Administration for bone …

Rezpegaldesleukin (Nktr-358) in New Onset Type 1 Diabetes Mellitus

L
Linda DiMeglio, MD
8 years - 45 years
All genders
Phase 2
Interventional
This Phase 2 study is a 2-arm, multi-center, double-masked, placebo-controlled, 2:1 randomized sequential trial design in new onset T1D participants (within 100 days of diagnosis). THIS STUDY IS ENROLLING BY INVITATION ONLY 

Inhale-1st: Technosphere Insulin (Afrezza) In Combination With Basal Insulin For Youth With Newly-Diagnosed Type 1 Diabetes

L
Linda DiMeglio, MD
10 years - 17 years
All genders
Phase 2
Interventional
INHALE-1st is a Phase 2, single-arm, multi-center, clinical study evaluating the safety and efficacy of Afrezza in combination with subcutaneously-injected basal insulin (BI) for youth 10 to THIS STUDY IS ENROLLING BY INVITATION ONLY 

Efficacy of the Omnipod 6 System Compared with the Omnipod 5 System in Individuals with Type 1 or Type 2 Diabetes and Suboptimal Glycemia

V
Viral Shah
14 years - 75 years
All genders
Interventional
This multi-center, randomized, cross-over trial will evaluate the efficacy of the Omnipod 6 System compared with the Omnipod 5 System in individuals with type 1 or type 2 diabetes and suboptimal glycemia.THIS STUDY IS ENROLLING BY INVITATION ONLY

Efficacy And Safety Of Medtronic 780G Automated Insulin Delivery System In Adults With Type 1 Diabetes And Gastroparesis

V
Viral Shah
18 years - 100 years
All genders
Interventional
The primary objective of this research is to study efficacy of Medtronic 780 G system in patients with type 1 Diabetes and gastroparesis (slow gastric emptying) compared to usual care (either multiple daily insulin injections or non Medtronic insulin pump therapy).THIS STUDY IS ENROLLING BY INVITATION ONLY - Study team …

Monitoring Volatile Organic Compound Profiles in Exhaled Breath to Noninvasively Detect Glycemic Events in Patients with Diabetes

M
Mangilal Agarwal
12 years - 19 years
All genders
Observational
Scosche Industries, Inc. has developed a completely noninvasive device which detects exhaled volatile organic compound (VOC) biomarkers. This wearable device was designed with the goal of early detection of hyperglycemia and possibly hypoglycemia in patients with diabetes. At this time, the device can be worn on the body (e.g. on …

Continuous Glucose Monitor Derived Glucose Dynamic Index as a Diagnostic Marker for Progression to Type 1 Diabetes (Dx-T1D)

V
Viral Shah
4 years - 100 years
All genders
Observational
This study is being done to develop a way to use information from a continuous glucose monitor (CGM) to predict a person’s progression through the Stages of Type 1 Diabetes (T1D).A CGM is a wearable device that continuously measures and displays a person’s blood sugar levels throughout the day and …
 Identification of Serum and Urine Biomarkers of Type 1 Diabetes

Identification of Serum and Urine Biomarkers of Type 1 Diabetes

C
Carmella Evans-Molina, MD
1 years - 95 years
Accepts healthy volunteer
All genders
What is the purpose of this study?The purpose of this study is to identify biomarkers (small molecules in the blood) that can predict those people at risk of developing Type 1 diabetes. THIS STUDY IS ENROLLING BY INVITATION ONLY - Potential participants will be recruited in various ways for different aims …

The Gut Microbiome in Type 1 Diabetes and Mechanism of Metformin Action

H
Heba Ismail
11 years - 18 years
All genders
Phase 2
Interventional
Obesity prevalence in persons with T1D has increased, which further complicates managementd risk for complications. The proposed study is relevant to public health because it helps us understand the role of the gut microbiome in disease pathophysiology in T1D youth withbesity as well as potential mechanisms to modify disease.

Pregnancy Data Repository to Assess Management of Type 1 Diabetes with Diabetes Technology (PRAM-T1D)

C
Christina M. Scifres, MD
18 years - 100 years
All genders
Observational
What is the purpose of this study?The study is being done because we want to learn more about how people with type 1 diabetes in the United States manage their diabetes during pregnancy. We will enroll pregnant individuals with type 1 diabetes to participate in the PRAM-T1D registry, which will …
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