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Found 10 Diabetes Mellitus, Type 1 trials

A listing of Diabetes Mellitus, Type 1 medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

 Identification of Serum and Urine Biomarkers of Type 1 Diabetes
C
Carmella Evans-Molina, MD
1 years - 40 years
Accepts healthy volunteer
All genders
The purpose of this study is to identify biomarkers (small molecules in the blood) that can predict those people at risk of developing Type 1 diabetes.
L
Linda DiMeglio, MD
8 years - 17 years
All genders
Phase 3
What is the purpose of this study?This study is the long-term extension of the PRV-031-001 (PROTECT) study. PROTECT is a Phase 3, randomized, double-blind, placebo-controlled, multinational, multi-center study to evaluate the efficacy and safety of teplizumab, a humanized, anti-CD3 monoclonal antibody, in children and adolescents ages 8 through 17 recently …
T
Tamara Hannon, MD
15 years - 17 years
All genders
We propose a study that incorporates mind-body skills with diabetes education specifically designed for adolescents with T1D.  To our knowledge, this is the first of such a study in adolescents with T1D.
L
Linda DiMeglio, MD
4 years - 12 years
All genders
The purpose of this research study is to measure how much of the study drug (Afrezza) gets into your bloodafter a single dose and measure how well it works to control your blood sugar level. We also want to make surethis study drug is safe for children and adolescents between …
A
Anna Neyman
7 years - 18 years
All genders
The aim of this study is to learn more about the long-term effectiveness of hybrid closed-loop system and verapamil in treating type 1 diabetes.
E
Emily Sims, MD
6 years - 40 years
All genders
Phase 2
Interventional
The goal of this clinical trial is to test a drug known as DFMO in people with Type 1 Diabetes (T1D). The main question[s] it aims to answer are: Does it reduce stress on the cells that make insulin? Does it preserve what is left of the body's insulin production? …
L
Linda DiMeglio, MD
8 years - 45 years
All genders
Researchers are looking for volunteers between 8-45 years of age who have been recently diagnosed with Type 1 diabetes mellitus (T1DM)ke part in a study identify a safe, metabolically favorable, dosing regimen of a treatment called siplizumab that targets the immune response and missing beta cell function that leads to …
H
Heba Ismail
11 years - 18 years
All genders
Phase 2
Interventional
Obesity prevalence in persons with T1D has increased, which further complicates managementd risk for complications. The proposed study is relevant to public health because it helps us understand the role of the gut microbiome in disease pathophysiology in T1D youth withbesity as well as potential mechanisms to modify disease.
C
Christina M. Scifres, MD
18 years - 100 years
All genders
Observational
What is the purpose of this study?The study is being done because we want to learn more about how people with type 1 diabetes in the United States manage their diabetes during pregnancy. We will enroll pregnant individuals with type 1 diabetes to participate in the PRAM-T1D registry, which will …
L
Linda DiMeglio, MD
30 months - 45 years
Accepts healthy volunteer
All genders
RationaleThe accrual of data from the laboratory and from epidemiologic and prevention trials hasved the understanding of the etiology and pathogenesis of type 1 diabetes mellitus (T1DM). Genetic and immunologic factors play a key role in the development of T1DM, andharacterization of the early metabolic abnormalities in T1DM is steadily …