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Found 32 results for Diabetes Mellitus, Type 2

A listing of Diabetes Mellitus, Type 2 medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Rare and Atypical Diabetes Network (RADIANT)

C
Carmella Evans-Molina, MD
1 years - 80 years
All genders
RADIANT aims to discover and define rare and atypical forms of diabetes among individuals and families, by investigating and defining their molecular and metabolic bases, and developing processes as well as a database and biorepository to enhance further understanding of atypical diabetes by the broader research community. These refined diagnoses will …

Denosumab for Type 1 Diabetes

C
Carmella Evans-Molina, MD
18 years - 50 years
All genders
Phase 1/2
Interventional
Researchers at City of Hope (California), University of Alabama at Birmingham, and Indiana University are studying a medication called denosumab as a potential treatment for people with type 1 diabetes. Denosumab, also known as Prolia, is a drug that has been approved by the Food and Drug Administration for bone …

Evolve: Evaluation of the Fully Closed Loop Omnipod System for Safety and Efficacy in Adults With Type 2 Diabetes

V
Viral Shah
18 years - 75 years
All genders
Interventional
A multi-center, 26-week randomized controlled trial (RCT) to evaluate the safety and efficacy of the fully closed loop Omnipod M System in adults with type 2 diabetes using basal/bolus insulin therapy or basal-only insulin therapy, with the primary endpoint after 15 weeks and secondary analysis at 26 weeks; followed by …

Prevalence of Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) in High-Risk Patients Presenting to Primary Care

R
Raj Vuppalanchi, MD
All genders
Observational
This study will provide the first comprehensive real-world prevalence data on MASLD in a primary care-based high-risk population, using validated non-invasive imaging. Results will inform evidence-based screening guidelines, support integration of FibroScan into PCP workflows, and facilitate early intervention to reduce progression to advanced liver disease. Identified predictors of significant …

Peer Support Groups for Youth with Diabetes

T
Tamara Hannon, MD
15 years - 25 years
All genders
Observational
Youth with type 1 or type 2 diabetes mellitus (T1D; T2D) from low socioeconomic backgrounds in rural western Kenya and in urban or rural Indiana struggle with poor glycemic control and have limited access to peer-support and ongoing diabetes education. The impact of peer-support and education groups that address social, …

Efficacy of the Omnipod 6 System Compared with the Omnipod 5 System in Individuals with Type 1 or Type 2 Diabetes and Suboptimal Glycemia

V
Viral Shah
14 years - 75 years
All genders
Interventional
This multi-center, randomized, cross-over trial will evaluate the efficacy of the Omnipod 6 System compared with the Omnipod 5 System in individuals with type 1 or type 2 diabetes and suboptimal glycemia.THIS STUDY IS ENROLLING BY INVITATION ONLY

Diabetes Prevention Programming for Women with a History of Gestational Diabetes (Positive Outcomes for Women (POW)

T
Tamara Hannon, MD
18 years - 99 years
Female
The purpose of this study is to offer women with a history of gestational diabetes access to diabetes prevention programming; their children 10 and older can participate.THIS STUDY IS ENROLLING BY INVITATION ONLY - Women will be recruited for this study in a variety of ways, including women participants in …

A Phase 3, Open-Label, Multicenter, Single-Arm Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Efficacy of Dulaglutide 3.0 Mg and 4.5 Mg in Pediatric Participants 10 to Less Than 18 Years of Age With Type 2 Diabetes Mellitus

T
Tamara Hannon, MD
10 years - 17 years
All genders
Phase 3
Interventional
The purpose of this study is to evaluate the safety, tolerability, pharmacokinetics, and efficacy of dulaglutide 3.0 mg and 4.5 mg in pediatric participants 10 to less than 18 years of age with T2DM.THIS STUDY IS ENROLLING BY INVITATION ONLY

Identification of Gut Microbiome and Metabolome Biomarkers in Diabetes

H
Heba Ismail
1 years - 75 years
All genders
Observational
What is the purpose of this study?The purpose of this study is to evaluate the gut microbiome and circulating microbial metabolites of children and adults with prediabetes and diabetes so we can compare the differences across different stages of diabetes but also across different forms of diabetes and different age …

Evaluation of Next Generation Sensors (Ngs) and Algorithm in Patients with Type 1 and Type 2 Diabetes

V
Viral Shah
2 years - 80 years
All genders
Observational
The purpose of this study is to collect data on the performance of sensor(s) each connected to/integrated with the transmitter(s) during 7-17 days of wear (approximately 170 to 410 hours) in subjects with type 1 or type 2 diabetes, 2-80 years of age.THIS STUDY IS ENROLLING BY INVITATION ONLY 
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