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Found 11 Small Cell Lung Cancer trials

A listing of Small Cell Lung Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Greg Durm, MD
18 years or above
All genders
Phase 3
Interventional
What is the purpose of this study?The main objective is to compare the efficacy of tarlatamab with standard of care (SOC) on prolonging overall survival (OS).THIS STUDY IS ENROLLING BY INVITATION ONLY - Consistent with most oncology trials, patients are not actively “recruited,” but are screened by their physician for …
G
Greg Durm, MD
18 years - 100 years
All genders
Phase 2
Interventional
What is the purpose of this study?This phase II trial studies the effects of temozolomide and atezolizumab as second or thirdwith small cell lung cancer that has spread to other places inhe body (metastatic) or has come back (recurrent). Chemotherapy drugs, such as temozolomide, work in different ways to stop …
R
Rohan Maniar
18 years or above
All genders
Phase 1/2
Interventional
What is the purpose of this study?Part 1: A first-in-human, open-label, Phase I dose escalation study of DSP107 monotherapy and combination therapy with atezolizumab in patients with advanced solid tumors. Part 2: Preliminary efficacy assessment of DSP107 in combination with atezolizumab in second or third line treatment of non small …
S
Shadia Jalal, MD
18 years - 100 years
All genders
What is the purpose of this study?This is pilot study to establish a rapid autopsy program in Small Cell Lung Cancer (SCLC) at the Indiana University Simon Comprehensive Cancer Center and outline the components necessary for tumor tissue collection. This proposal is a collaboration between scientists, lung cancer physicians, pathologists, …
C
Catherine Sears, MD
40 years or above
All genders
Observational
What is the purpose of this study?This study evaluates the how addition of the Nodify XL2 test result impacts the clinicalgement of newly identified solid lung nodules assessed as low to moderate risk of cancer.THIS STUDY IS ENROLLING BY INVITATION ONLY - Consistent with most oncology trials, patients are not …
N
Naoyuki Saito, MD
18 years - 100 years
All genders
Phase 3
What is the purpose of this study?This phase III trial studies magnetic resonance imaging (MRI) surveillance and prophylactic cranial irradiation (PCI) to see how well they work compared to MRI surveillance alone in treating patients with small cell lung cancer. MRI scans are used to monitor the possible spread of …
K
Kevin Shiue
18 years - 100 years
All genders
Phase 3
What is the purpose of this study?This phase III trial compares the effect of stereotactic radiosurgery to standard of care memantine and whole brain radiation therapy that avoids the hippocampus (the memory zone of the brain) for the treatment of small cell lung cancer that has spread to the brain. …
R
Rohan Maniar
18 years - 100 years
All genders
Phase 2
What is the purpose of this study?This phase II Expanded Lung-MAP treatment trial tests how well amivantamab-subcutaneous (SC) works in treating patients patients with MET amplification non-small cell lung cancer. Amivantamab-SC is a drug that reduces extra copies of the MET gene, a change present in your tumor. Giving amivantamab-SC …
V
Vijaya L. Kakani, MD
18 years - 100 years
All genders
Phase 3
Interventional
What is the purpose of this study?This study will assess if adding sacituzumab tirumotecan with pembrolizumab after surgery is effective in treating NSCLC for participants not achieving pathological complete response. The primary hypothesis of this study is sacituzumab tirumotecan plus pembrolizumab is superior to pembrolizumab monotherapy with respect to disease …
J
Jonathan L. Berkowitz, MD, PhD
18 years - 100 years
All genders
Phase 3
Interventional
What is the purpose of this study?To evaluate the efficacy of divarasib compared with KRAS G12C inhibitors (sotorasib or adagrasib)To evaluate the efficacy of divarasib compared with KRAS G12C inhibitors (sotorasib or adagrasib)To evaluate, from the participant's perspective, the functioning and impact of key disease-related symptoms of participants treated with …
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