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Found 54 Acute Lymphocytic Leukemia trials

A listing of Acute Lymphocytic Leukemia medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

A Phase 1 Trial of Targeted Immunotherapy with Daratumumab Following Myeloablative Total Body Irradiation (TBI)-Based Conditioning and Allogeneic Hematopoietic Cell Transplantation in Children, Adolescents and Young Adults with High-Risk T-Cell Acute Lymphoblastic Leukemia and Lymphoma

J
Jodi Skiles
1 years - 39 years
All genders
Phase 1
What is the purpose of this study?A Phase I trial to determine the safety of targeted immunotherapy with daratumumab (DARA) IV after total body irradiation (TBI)-based myeloablative conditioning and allogeneic hematopoietic cell transplantation (HCT) for children, adolescents, and young adults (CAYA) with high risk T-cell acute lymphoblastic leukemia (T-ALL) or …
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Investigating Levocarnitine for Reducing Liver Issues in Leukemia Treatment

R
Rachael Schulte
15 years - 40 years
All genders
This study investigates whether adding levocarnitine to chemotherapy regimens can reduce liver problems, specifically conjugated hyperbilirubinemia, in adolescents and young adults with Acute Lymphoblastic Leukemia (ALL). Conjugated hyperbilirubinemia is a condition where there is too much bilirubin, a substance made during the breakdown of red blood cells, in the blood. …
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Study of Treatments for Relapsed B-Cell Acute Lymphoblastic Leukemia

S
Sandeep Batra, MD
1 year - 30 years
All genders
Phase 2
Interventional
This study investigates the effects of two investigational medications, blinatumomab and nivolumab, in patients with B-cell acute lymphoblastic leukemia (B-ALL) that has relapsed. B-ALL is a type of cancer that affects the white blood cells. The study includes patients with Down syndrome and aims to compare the outcomes of using …
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Investigating Additional Treatments for Infant Blood Cancer

A
Amanda J. Saraf, DO
1 year or below
All genders
Phase 2
This study investigates the addition of investigational medication and investigational immunotherapy to the usual chemotherapy for infants with newly diagnosed acute lymphoblastic leukemia (ALL). ALL is a type of cancer where the bone marrow makes too many immature lymphocytes (a type of white blood cell). In this study, the researchers …
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Study on Adding an Investigational Medication to Chemotherapy for High-Risk Leukemia

S
Sandeep Batra, MD
1 year - 25 years
All genders
Phase 3
Interventional
This study investigates the effectiveness of adding an investigational medication to post-induction chemotherapy for patients with High-Risk B-cell Acute Lymphoblastic Leukemia (B-ALL). It also examines outcomes for patients with mixed phenotype acute leukemia (MPAL) and B-lymphoblastic lymphoma (B-LLy) treated with standard chemotherapy. B-ALL is a type of cancer that affects …
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Investigation into the Interaction Between Genes and Stress in Etiology of Depression in Interns

J
Joanna Chambers, MD
18 years - 100 years
Accepts healthy volunteer
All genders
Medical internship is a period filled with predictable and high levels of chronic uncontrolled stress. Rates of depression among interns are elevated compared to the general population. In this study, we aim to utilize the predictable and consistent stress of internship to investigate the relationship between stress, genes and depression …
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Understanding hair follicle structure & pigmentation genetics: expression/methylation differences found in hair growth location.

S
Susan Walsh
18 years - 100 years
Accepts healthy volunteer
Male
The purpose of this study is to research on the genes that cause different hair colors in an individual using the genetic information extracted from the hair samples the study participants provide.
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Online activities among transgender community

N
Nathan Ensmenger
13 years or above
Accepts healthy volunteer
Transgender
What is the purpose of this study?The purpose of this study is to observe how transgender people in the United States use online spaces and to provide analysis of how trans people create their own knowledge about intersectional relations of gender through their speech and practices on the Internet. THIS …
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Parkinson's Progression Markers Initiative 2.0 Remote Study

T
Tatiana Foroud
30 years - 100 years
All genders
What is the purpose of this study?The purpose of PPMI 2.0 Remote is to find out if information collected remotely (by internet, mail, home visits, or phone applications) can help identify individuals at an increased risk of developing Parkinson’s Disease.  Identifying at-risk individuals may also help researchers learn how to …
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Case Studies of Rare Gene Variants Linked to Parkinson’s Disease

T
Tatiana Foroud
18 years - 100 years
All genders
What is the purpose of this study?Parkinson disease (PD) is s the second most common movement disorder, occurring in 1-3% of the population. It is a complex condition with varied symptomatology, age of onset, and rate of progression. Much has been learned about PD in the last several decades including …
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