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Found 31 Liver Disease/Disorder trials

A listing of Liver Disease/Disorder medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

OnX Liver Assessment Solution Clinical Study

R
Raj Vuppalanchi, MD
22 years - 80 years
All genders
Interventional
What is the purpose of this study?This protocol’s primary aim is to assess the performance of the OnX exam on patients with suspected or confirmed liver disease with the goal of comparing the OnX output stiffness estimates to FibroScan® liver stiffness measurements. Our primary objectives are to assess whether the …
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A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Study to Evaluate the Safety and Efficacy of Fazirsiran in the Treatment of Alpha-1 Antitrypsin Deficiency-Associated Liver Disease With METAVIR Stage F1 Fibrosis

R
Raj Vuppalanchi, MD
18 years - 75 years
All genders
Phase 3
Interventional
Why is this study being done?In some people, the liver makes an abnormal version of the alpha-1 antitrypsin (AAT) protein, called Z-AAT. Making an abnormal version of the AAT protein can result in liver disease as Z-AAT builds up in liver cells, which leads to liver problems such as liver …
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Characterization of Patients Referred to Indiana University for Evaluation and Management of Suspected Nonalcoholic Fatty Liver Disease

N
Niharika Samala, MD
18 years - 100 years
All genders
What is this study about?Patients with nonalcoholic fatty liver disease have varied etiologies, associated risk factors and disease severity.  One purpose of this study is to determine the possible etiological factors, risk factors, and disease severity of all patients referred to Digestive and Liver Diseases Clinics for presumed NAFLD.  Another …
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Simultaneous Prospective Kidney Transplant assessment in Combined Liver Kidney Candidates (RECOVERY) Study

M
Muhammad Jan
K
Kenneth Lim
18 years - 100 years
All genders
The purpose of the study is to determine how much a persons kidney function recovers after receiving a simultaneous liver kidney transplant. We are interested to see if a liver transplant alone makes it unnecessary to perform a kidney transplant. 
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Microbiome alterations in the setting of intestinal failure associated liver disease

K
Katie Huff
18 months or below
All genders
What is the purpose of this study?Neonates who require prolonged IV nutrition (TPN) are at risk for such complications as intestinal failure associated liver disease (IFALD). In addition, it is also known that TPN and lack of nutrition through the GI tract influences the intestinal microbiome or bacteria present in …
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National Liver Cancer Screening Trial (TRACER)

N
Naga Chalasani, MD
18 years - 85 years
All genders
What is this study about?The National Liver Cancer Screening Trial is an adaptive randomized phase IV Trial comparing ultrasound-based versus biomarker-based screening in 5500 patients with cirrhosis from any etiology or patients with chronic hepatitis B infection. Eligible patients will be randomized in a 1:1 fashion to Arm A using …
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Effect of the HCC-EduLink Intervention

L
Lauren Nephew
18 years - 100 years
All genders
The objective of this study is to pilot test a multi-level intervention designed to address patient- and system-level social and structural determinants of health (SSDOH) variables and facilitate access to curative hepatocellular carcinoma (HCC) therapies, including liver transplantation and resection, in a cohort of Black patients with Barcelona Clinic Liver …
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Autoimmune Liver Disease Network for Kids (A-LiNK): Using Patient Data to Transform Care and Improve Outcomes for Children, Adolescents, and Young Adults With Autoimmune Liver Disease

K
Kyla Tolliver
1 years - 17 years
All genders
Observational
What is the purpose of this study?The Autoimmune Liver disease Network for Kids (A-LiNK) is a multi-institutional group with the mission to deliver the best care to kids with pediatric autoimmune liver disease (AILD).This study will establish a shared clinical registry and a learning health network for the participating sites …
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Creation of specimen biorepository and analysis of transcriptome and metabolome as potential mechanism in intestinal failure associated liver disease in neonate

K
Katie Huff
100 years or below
All genders
We will build a biorepository of blood and urine samples correlated with clinical data in neonates receiving parenteral nutrition in order to study IFALD
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Measuring Patient Reported Needs in Outpatient Liver Disease Management

A
Archita Desai, MD
18 years - 100 years
All genders
Observational
What is the purpose of this study?Patients with chronic liver disease (CLD) are biopsychosocially complex and represent a vulnerable population at high risk for poor health-related outcomes. Beyond their primary liver disease, individuals with CLD often have unmet social needs which serve as important social determinants of health (SODH). For …
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