CT-Based Muscle Changes in a Retrospective Cohort of Patients
Investigating Muscle Changes in Trauma Patients Using Special Images Taken of the Body
Todd McKinley, MD
Primary Investigator
Brief description of study
The purpose of this study is that patients who have muscle deterioration after experiencing a traumatic injury will have worse long term outcomes than patients who do not have muscle deterioration. We plan to prove that using the change in muscle mass on serial CT scans can be used as a tool to identify patients who are at risk of a poor long term outcome and intervene in their care through aggressive nutritional and rehabilitation support in hopes of improving their recovery.
Detailed description of study
We plan to prove that using the change in muscle mass on serial CT scans can be used as a tool to identify patients who are at risk of a poor long term outcome and intervene in their care through aggressive nutritional and rehabilitation support in hopes of improving their recovery. Once a patient has been identified as meeting the inclusion criteria, they will then be called to see if they would be willing to participate in our study, which involves a one-time phone contact (in which 3 surveys are completed on the phone: SF36, PROMIS Physical Function and PROMIS Pain Interference) as well as asking questions if the patient had been treated for an infection or had any reoperations. The phone call will last approximately 20 minutes. Once the phone surveys are completed, the study team will then go back to the patient's chart to perform the CT measurements and obtain additional information from the subject's medical record.
Eligibility of study
You may be eligible for this study if you meet the following criteria:
- Conditions: Traumatic injury, Muscle deterioration
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Age: 18 years - 55 years
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Gender: All
Inclusion Criteria
Polytraumatized patients with ISS scores >18 from January 1, 2013-December 31, 2017
Patients with two or more CT scans of the abdomen and pelvis within a 6 month period
Patients who respond to the phone call/mail surveys to obtain survey data
Exclusion Criteria
Patients with ISS scores Patients with less than two CT scans of the abdomen and pelvis
People who fail follow up or who fail to respond to phone calls/mail surveys.
This study investigates muscle changes in people who have had a traumatic injury. The purpose is to see if muscle deterioration affects recovery. Muscle deterioration means losing muscle mass, which can happen after a serious injury. The study looks at CT scans, which are special images taken of the body, to track muscle changes.
Participants will have their CT scans reviewed to see if their muscle mass changes over time. The study uses these scans to find out if changes in muscle mass can predict how well someone recovers. This means looking at the pictures to see if losing muscle affects getting better after an injury.
- Who can participate: Adults who have had a serious injury with an ISS score over 18 and have had at least two CT scans of the abdomen and pelvis within six months can participate. They must also respond to surveys by phone or mail.
- Study details: Participants will have their CT scans reviewed to observe changes in muscle mass. They will also need to respond to surveys to provide additional information.
