Role of Aging in GCN2-dependent wound healing
D
Dan Spandau
Primary Investigator
Recruiting
20 years - 100 years
All
Phase
N/A
1 Location
Brief description of study
What is the purpose of this study?
When a normal healthy adult's skin is wounded, their skin usually heals without difficulty; however, if a person damages their skin while they are sick or if they have a chronic disease, the wound may not heal as quickly. Also, as we age, the wound healing process is slowed and delayed. The purpose of this study is to examine acute wound healing to determine whether a specific mechanism in how we respond to stress plays a role in the aging-related decline in wound healing. It will determine whether defects in this stress response occur with age and if it suppresses wound healing.
Detailed description of study
Reccruiting Veterans Only
Eligibility of study
You may be eligible for this study if you meet the following criteria:
- Conditions: Healthy
-
Age: 20 years - 100 years
-
Gender: All
Inclusion Criteria
1.Age: either between 20-28 years old or at least 65 years old
2.Good general health
Exclusion Criteria
1. Diagnosis of diabetes mellitus
2. History of abnormal scarring
3. History of immunosuppression
4. History of abnormal skin infections
5. Allergies to xylocaine anesthetic
6. History of bleeding disorders
7. Use of anticoagulants
8. Unable to understand informed consent document
Additional Information:
Updated on
06 Mar 2025.
Study ID: DERM-IIR-GCN2, 1909990266
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