Effects of Skeletal Trauma on the Metabolome

T
Todd McKinley, MD

Primary Investigator

T
Todd Owen Mckinley

Primary Investigator

Administratively Closed
18 years - 55 years
All
Phase N/A
25 participants needed
2 Locations

Brief description of study

The purpose of this study is to assess the effects of skeletal trauma on the human metabolome, or the pathways by which the body creates, stores, and breaks down energy.

Detailed description of study

Additional blood will be drawn at the same time as participants' standard pre-operative and postoperative labs.
Standard of care surgical treatment will be performed.
At each post-operative visit, participants will complete two questionnaires regarding overall function and ankle function.
Researchers will review participants' medical records for this study.

Eligibility of study

You may be eligible for this study if you meet the following criteria:

  • Conditions: fracture, broken bone, metabolism
  • Age: 18 years - 55 years
  • Gender: All

Individuals between 18 and 55 years of age, with a scheduled surgery for a closed pilon or closed tibial plateau fracture.
Individuals with diabetes mellitus will not be eligible.
Pregnant and/or breastfeeding women will not be eligible.

Updated on 27 May 2025. Study ID: ORTHO-IIR-METABOLIC-RESPONSE, 1907089469

Interested in the study?

Select a study center that’s convenient for you, and get in touch with the study team.

Contact a study center