Buffered vs. Unbuffered Local Anesthesia in Mandibular Molars Diagnosed with Symptomatic Irreversible Pulpitis: A Controlled, Randomized Double-blind Study
K
Kenneth Spolnik
Primary Investigator
Not Recruiting
18 years - 80 years
All
Phase
N/A
40 participants needed
1 Location
Brief description of study
The purpose of this study is to determine whether one type of anesthetic (numbing medicine) will work better at numbing the nerve in a tooth than using a different type of anesthetic. A second purpose is to see if the time needed to numb the nerve in a tooth is different between the two anesthetics.
Potential research subjects will be pooled from patients scheduled to receive an endodontic evaluation and/or a nonsurgical root canal therapy (NSRCT) in the Graduate Endodontic clinic at Indiana University School of Dentistry.
Eligibility of study
You may be eligible for this study if you meet the following criteria:
- Conditions: pulpitis,irreversible pulpitis
-
Age: 18 years - 80 years
-
Gender: All
Inclusion Criteria:
- Male or Female
- Between the ages of 18 and 80 years old
- Have the ability and the willingness to independently consent to treatment and study participation.
- Must have an uncomplicated medical history (ASA I and II).
- Must be experiencing signs of irreversible pulpitis (an exaggerated response to cold that lingers longer than 10 seconds) in a mandibular molar at the time of conducting the study.
Exclusion Criteria:
- Allergies to local anesthetics/sulfites (confirmed or self-reported).
- Currently pregnant
- The use of acetaminophen or short-acting NSAIDs (i.e.-Ibuprofen) within the previous 6 hours; or longer acting NSAIDs (i.e.- naproxen) within the previous 16 hours.
- Requiring nitrous oxide during treatment.
- Unhealthy injection area with other pre-existing conditions or infections
- A negative response to cold in the proposed treatment tooth.
Updated on
01 Aug 2024.
Study ID: 11447
