Simultaneous Prospective Kidney Transplant assessment in Combined Liver Kidney Candidates (RECOVERY) Study
Investigating Kidney Function Recovery in Patients Undergoing Both Liver and Kidney Transplants
Muhammad Jan
Primary Investigator
Brief description of study
Detailed description of study
- A nuclear medicine scan uses small amounts of radiation to create pictures of your kidneys and takes approx. 40 minutes to complete
- The results of the second scan will be compared to the results of the first scan to determine how much your kidney function has improved. Study participation lasts approx. 10 months
Eligibility of study
You may be eligible for this study if you meet the following criteria:
- Conditions: Liver disease, Acute kidney injury (AKI)
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Age: 18 years - 100 years
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Gender: All
- Must be 18 years of age or older
- Must be diagnosed with end stage liver disease and acute kidney injury (AKI)
- Will be having SLK surgery at Indiana University (IU) School of Medicine /IU Health Transplant as part of standard medical care.
- Unstable patients (e.g. in the ICU or those who are on Continous Renal Replacement Therapy (CRRT) who cannot complete the nuclear medicine scan or those with AKI on Hemodialysis
- Prior history of any solid organ transplant.
- Those who are currently pregnant or breast feeding.
This study investigates how kidney function recovers after a person receives both a liver and a kidney transplant. The purpose of this study is to see if having a liver transplant alone can improve kidney function enough that a kidney transplant might not be needed. This study is for people with acute kidney injury, which is a sudden decrease in kidney function, and end-stage liver disease, which is the final stage of chronic liver disease.
Participants will have two nuclear medicine scans. A nuclear medicine scan is a test that uses small amounts of radiation to create pictures of the kidneys and takes about 40 minutes. The first scan happens before the transplant, and the second scan happens 10 months later. The results of these scans will be compared to see how much kidney function has improved.
- Who can participate: Participants must be 18 years or older and have end-stage liver disease and acute kidney injury. They must be scheduled for a simultaneous liver-kidney transplant at Indiana University School of Medicine.
- Study details: Participants will undergo two nuclear medicine scans to assess kidney function recovery. These scans use small amounts of radiation to create images of the kidneys.
- Study timelines: The study will last 10 months.
