Delirium and Neuropsychological Recovery Among Emergency General Surgery Survivors
M
Malaz Boustani, MD
Primary Investigator
Enrolling By Invitation
65 years and older
All
Phase
N/A
528 participants needed
5 Locations
Brief description of study
This study will evaluate the usefulness of the Emergency General Surgery (EGS) Delirium
Recovery Model. It is hypothesized that the cognitive, physical and psychological recovery ofder EGS delirium survivors will be improved through the use of the EGS Delirium Recoverydel. Participants can expect to be on the study for 18 months.
Detailed description of study
This is a multi-site, two-arm, single-blinded randomized controlled clinical trial tovaluate the efficacy of the EGS Delirium Recovery Model to improve the cognitive, physicald psychological recovery of older EGS delirium survivors. At or near the time of discharge,d participants will be randomized to receive the EGS-Delirium Recovery Model or usual. The hypothesis is that, after 18 months, older EGS delirium survivors who aredomized to the EGS Delirium Recovery Model will experience more favorable cognitive,hysical and psychological recovery in comparison to those randomized to usual care.
Eligibility of study
You may be eligible for this study if you meet the following criteria:
- Conditions: Delirium
-
Age: 65 Years
-
Gender: All
Inclusion Criteria:
- Adult age 65 years and older
- Admitted to one of the participating hospitals
- Undergone an abdominal surgery in an emergency or unplanned fashion (e.g. partialy, small bowel resection, repair of peptic ulcer disease, lysis of adhesions,y)
- English-speaking
- Able to provide consent or have a legally authorized representative to provide consent
- Access to a telephone or an internet connected computer or smart device
- Discharged to home or sub-acute rehabilitation
- At least one episode of delirium in the period prior to discharge from acute care
Exclusion Criteria:
- A self-reported diagnosis of cancer with short life expectancy
- Current chemotherapy or radiation therapy confirmed by electronic medical record
- A history of dementing illnesses and other neurodegenerative disease such asAlzheimer's disease (AD), Parkinson disease, or vascular dementia, or currentdementia medication, or ruled out by Functional ActivitiesQuestionnaire (FAQ) score defining dementia; a history of significant traumatic brainjury
- Have any spinal cord injury with persistent neurologic deficit at the time of study
- Incarcerated or homeless at the time of study enrollment
- Acquired neurologic injury (stroke, traumatic brain injury, cerebral edema/swelling,brain injury, or any other acute/subacute severe neurologic deficit) as thedmitting diagnosis or a new event during the course of hospitalization (confirmed by EMR)
- History of alcohol misuse or abuse within the last three months, defined as ≥8 drinksweek on average for women or ≥15 drinks per week for men (confirmed by self-reportR)
- History of drug abuse within the last 3 months confirmed by EMR or self-report withDrug Abuse and Screening Test (DAST-10) score ≥ 3.
Updated on
01 Aug 2024.
Study ID: 2022-0545
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