FT576 in Subjects With Multiple Myeloma
R
Rafat Abonour, MD
Primary Investigator
Enrolling By Invitation
18 years and older
All
Phase
1
168 participants needed
3 Locations
Overview
This is a Phase I dose-finding study of FT576 as monotherapy and in combination with thebody daratumumab in multiple myeloma (MM). The study will consist of a
dose-escalation stage and an expansion stage.
Eligibility
You may be eligible for this study if you meet the following criteria:
-
Conditions:
Multiple Myeloma, Myeloma
-
Age: 18 Years
-
Gender: All
- Abbreviated inclusion criteria:
Diagnosis of r/r MM with measurable disease by at least one of the following:
- Serum M-protein ≥1.0 g/dL
- Urine M-protein ≥200 mg/24 hours
- Involved serum free light chain level ≥10 mg/dL, with an abnormal kappa-lambda ratiohe serum M-protein <1.0 g/dL and/or urine M-protein <200 mg/24 hours
- Regimens A and A1: MM relapsed or progressed after ≥3 prior approved therapies,uding an IMiD, proteosome inhibitor, and anti-CD38 mAb
- Regimens B and B1: MM relapsed or progressed after ≥2 prior approved therapies,uding an IMiD and proteosome inhibitor
Updated on
15 May 2024.
Study ID: FT576-101, CTO-FT576-101, 12297
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