Preventing cervical cancer in HIV-infected Kenyan and Ugandan women
Overview
The first study goal is to evaluate HR-HPV DNA testing of self-collected vaginal swabs combined with VIA in screening for cervical cancer in HIV-infected women living in Kenya or Uganda.
The second study goal is to determine if aflatoxin is a risk factor for cervical cancer among HIV-infected Kenyan and Ugandan women.
Description
This study aims to better understand the natural history of HPV infection (HPV is a virus that can cause cervical cancer) and cervical cancer and to determine how to best screen for cervical cancer and to identify cofactors in addition to HIV that are involved. It also aims to understand if aflatoxin (a chemical produced by mold commonly found in Uganda and Kenya) is an additional risk factor for cervical cancer among HIV-infected Kenyan and Ugandan women.
Eligibility
You may be eligible for this study if you meet the following criteria:
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Conditions:
HIV, Cervical Cancer
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Age: Between 21 Years - 60 Years
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Gender: Female
Inclusion Criteria:
- Kenyan women living in or within 30 km of Eldoret who present for cervical cancer screening at the CCRP, and Ugandan women who live within 30 km of Mulago who present for cervical cancer screening at the UCI/IDI clinic
- Willing to return for four total visits over a three-year total period
Exclusion Criteria:
- Women who are currently pregnant
- Inability to consent due to mental or physical disability, or a medical illness that has rendered the patient unable to attend annual visits.
Updated on
02 May 2024.
Study ID: 11449, U54-IUSCCC-0761
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