The GenECT Study
Susan Conroy, MD PhD
Primary Investigator
Brief description of study
Why is this study being done?
This study will advance our understanding of the genetic etiology of severe MDD which, in turn, will motivate the development of new and more effective treatment strategies for this burdensome and difficult to treat condition. In addition, it will identify genetic factors that can help distinguish which patients are good candidates for ECT before initiating treatment.
Detailed description of study
What will happen during the study?
Genetic analysis of participants treated with ECT will identify gene loci associated with severe mood disorders, including major depressive disorder (MDD) or bipolar disorder (BPD), at genome-wide significance in comparison to participants with milder mood disorders.
THIS STUDY IS ENROLLING BY INVITATION ONLY
Eligibility of study
You may be eligible for this study if you meet the following criteria:
- Conditions: Major depressive disorder, Bipolar disorder, Mood disorder
-
Age: 18 years - 100 years
-
Gender: All
Inclusion Criteria:
- Subject is currently undergoing ECT or evaluation to receive ECT or has received ECT in the past
- Subject has a lifetime diagnosis of MDD or BPD.
Exclusion Criteria:
- Subject has a history of significant head trauma with loss of consciousness.
- Subject has a lifetime diagnosis of a primary psychotic disorder (e.g., schizophrenia or schizoaffective disorder).
