The Cardiogenic Shock Working Group Registry

Cardiogenic Shock Outcomes Registry

O
Onyedika Ilonze

Primary Investigator

Enrolling By Invitation
18 years - 100 years
All
Phase N/A
200 participants needed
2 Locations

Brief description of study

The Cardiogenic Shock Working Group Registry is a multicenter registry of patients admitted for cardiogenic shock. The objective of the registry is to collect limited data set clinical variables from the medical records from multiple institutions and centralize this data to a single registry for analysis of clinical outcomes. Lack of a central database for cardiogenic shock has limited analysis of cardiogenic shock to small group studies; the construction of a large collaborative database will provide the foundation for higher-power analysis in the future.  
 
THIS STUDY IS ENROLLING BY INVITATION ONLY - A review of all medical records will take place in order to evaluate whether subject meets inclusion/exclusion criteria. The records that are reviewed will be based on the protocol’s listed inclusion exclusion criteria. Patients with cardiogenic shock will be approached for consent to participate in the prospective arm of the study. All eligible subjects may be approached any time during Index Hospitalization and up to 40 days post discharge.

Detailed description of study

The objective of the registry is to collect de-identified clinical variables from the medical records and follow-up phone calls of shock patients from multiple institutions and centralize this data to a single registry for analysis of clinical outcomes. Lack of a central database for cardiogenic shock has limited analysis of cardiogenic shock to small group studies; the construction of a large collaborative database will provide the foundation for higher-power analysis in the future.

Eligibility of study

You may be eligible for this study if you meet the following criteria:

  • Conditions: Cardiogenic shock
  • Age: 18 years - 100 years
  • Gender: All

Inclusion Criteria
Cardiogenic Shock defined by at least one of the two categories below:
1.     At least 2 of the following concurrently at any point during the index hospitalization:
•    MAP 30mmHg drop in MAP from baseline
•    SBP 30mmHg drop in SBP from baseline
•    Pulse > 100
•    Cardiac Index •    PAPI •    Cardiac Power Output ≤ 0.6
2.     Requires the use of at least 1 vasopressor, inotrope, or acute mechanical circulatory support device to maintain values above the above targets.

Post-cardiotomy patients must meet the inclusion criteria 72 hours after their surgery to be included in the registry. 
Patients may be enrolled in other studies while being included in the registry.

 

This study investigates cardiogenic shock, a condition where the heart suddenly can't pump enough blood to meet the body's needs. The purpose of this study is to gather information from patients with cardiogenic shock to understand their health outcomes better.

Participants in the study will have their medical records reviewed and may be contacted for follow-up phone calls. This information will be collected from multiple hospitals and combined into a single database to help researchers analyze the outcomes of cardiogenic shock.

  • Who can participate: Adults with cardiogenic shock who have a significant drop in blood pressure or need specific support to maintain blood pressure may qualify. Post-cardiotomy patients must meet criteria 72 hours after surgery.
  • Study details: This is a registry study focused on collecting data. Participants will have their medical records reviewed and may be contacted for follow-up phone calls. No changes to treatment will occur; this is an observational study.
  • Study timelines and visits: This study does not have a specific timeline as it involves ongoing data collection and analysis. No visits are required for this study as it involves data collection and follow-up phone calls.
Updated on 17 Sep 2025. Study ID: KIC-IIR-GUGLIN-CSWG-REGISTRY, 11782
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Interested in the study?

This study is accepting only persons who receive care at a certain clinic or doctor or who are part of an invited group. Questions about this study can be directed to the study team listed in the description or contact your doctor to see if you are eligible.

Accepting Referrals by Invitation Only