MRI Assessment of Cerebrospinal Fluid Circulation after Acute Spinal Cord Injury
G
Gordon Mao
Primary Investigator
Enrolling By Invitation
18 years - 80 years
All
Phase
N/A
5 participants needed
1 Location
Brief description of study
What is this study about?
This study will use MRI technology before and after surgery to study the changes in the CSF flow. This may help increase the understanding of how those changes play a role in patients’ long-term recovery. This study is being done to help increase the understanding of the underlying mechanisms of traumatic spinal cord injury and the role that CSF flow may play in patients’ long-term recovery. The additional neck sequence is FDA approved and safe.
THIS STUDY IS ENROLLING BY INVITATION ONLY - Patients who have a traumatic spinal cord injury requiring surgical treatment will be identified and recruited by the principal investigator and may be approached during their preoperative clinical visit at IUH Methodist hospital for consent to participate in the study.
Detailed description of study
What happens during the study?
Patient will undergo 3 cervical noncontrast MRIs for this study, all of which will include the exact same MRI sequences that consists of the usual standard of care sequences and a single extra research sequence (FDA approved for patient safety) that will take 3-5 additional minutes.
Patient will undergo 3 cervical noncontrast MRIs for this study, all of which will include the exact same MRI sequences that consists of the usual standard of care sequences and a single extra research sequence (FDA approved for patient safety) that will take 3-5 additional minutes.
1)the initial MRI cervical spine obtained on admission/arrival to Methodist Hospital, prior to spinal intervention/surgery
2)follow up MRI at 28-35 days after surgery obtained at normal 1 month follow up clinic appointment
3)follow up MRI at 90-120 days after surgery obtained at normal 3-4 months follow up clinic appointment
Eligibility of study
You may be eligible for this study if you meet the following criteria:
- Conditions: Traumatic spinal cord injury, SCI
-
Age: 18 years - 80 years
-
Gender: All
Inclusion Criteria
• Incomplete or complete SCI (ASIA A-D) of the cervical and thoracic spine
• Patient agreeable to and underwent spinal surgical intervention to treat SCI
• Age 18-80 years old at time of injury
• Incomplete or complete SCI (ASIA A-D) of the cervical and thoracic spine
• Patient agreeable to and underwent spinal surgical intervention to treat SCI
• Age 18-80 years old at time of injury
Exclusion Criteria
• Patients who refused or did not quality for spinal surgical intervention
• Patient with biomedical implants who cannot undergo any form of MRI imaging
• Patients who refused or did not quality for spinal surgical intervention
• Patient with biomedical implants who cannot undergo any form of MRI imaging
Updated on
29 Apr 2025.
Study ID: SNEU-IIR-CSF-FD, 20216
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