Analysis of Senescent Markers in Periodontal and Periimplant Tissue
C
Chandni Batra
Primary Investigator
Enrolling By Invitation
18-100 years
All
Phase
N/A
100 participants needed
1 Location
Brief description of study
The aim of our study is 1) to analyze the level of senescence markers in periodontally healthy and diseased gingival tissue;
2) to analyze the level of senescence markers in periodontal and periimplant diseased gingival tissues and reveal the association between cellular senescence or ageing on progression of periodontal disease and periimplantitis and;
3) to analyze associations between levels of senescence markers and smoking status, body mass index (BMI), diabetes status and kidney disease.
2) to analyze the level of senescence markers in periodontal and periimplant diseased gingival tissues and reveal the association between cellular senescence or ageing on progression of periodontal disease and periimplantitis and;
3) to analyze associations between levels of senescence markers and smoking status, body mass index (BMI), diabetes status and kidney disease.
Detailed description of study
To
our knowledge, no study has been performed to assess the levels of senescence
markers in human gingival periodontal and periimplant tissues. Thus, the aim of
our study is 1) to analyze the level of senescence markers in periodontally
healthy and diseased gingival tissue; 2) to analyze the level of senescence
markers in periodontal and periimplant diseased gingival tissues and reveal the
association between cellular senescence or ageing on progression of periodontal
disease and periimplantitis and; 3) to analyze associations between levels of
senescence markers and smoking status, body mass index (BMI), diabetes status
and kidney disease.
Eligibility of study
You may be eligible for this study if you meet the following criteria:
- Conditions: gingivitis
-
Age: Between 18 Years - 100 Years
-
Gender: All
Inclusion Criteria:
- · Persons willing to participate via signed informed consent· ASA class I or II· Age >18 years old· All patients receiving any type of Periodontal or Peri-implant surgery· Willingness to undergo study procedures
Exclusion Criteria:
- · Pregnancy or nursing woman (Note: no pregnancy test will be required as the Periodontal Department at IUSD does not perform non-emergency treatment on anyone who self-reports they are pregnant. This study will follow their policy on allowing self-reporting of pregnancy/)· Active dental infection noted at the time of surgery
Updated on
01 Aug 2024.
Study ID: 17678; OHRI-IIR-17678
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