EXAMINING THE ROLE OF ALLOSTATIC LOAD IN RACIAL DISPARITIES IN INTRINSIC BREAST CANCER SUBTYPE AND AS A PROGNOSTIC MARKER

T
Tarah Ballinger, MD

Primary Investigator

Enrolling By Invitation
18 years - 100 years
All
Phase N/A
10 participants needed
4 Locations

Brief description of study

What is the purpose of this study?
The main purpose of this study is to better understand the relationship between stress, race, and breast cancer.
 
THIS STUDY IS ENROLLING BY INVITATION ONLY - Consistent with most oncology trials, patients are not actively “recruited,” but are screened by their physician for appropriate clinical trial(s) at the time of their routine clinic visit. Occasionally, a patient may be a self-referral or physician referral, but are still screened for appropriate clinical trials at the time of their routine clinic visit. PI and staff may send copies of relevant consent forms to these patients to look over prior to actually consenting or enrolling them. This may take place at the patient's visit at which the consent is presented or the patient's next visit to the outpatient hematology/oncology clinic. 
 
Interested in participating? For more information about this research study or other cancer-related clinical trials at IU Simon Comprehensive Cancer Center, please contact:
IU Clinical Trials Office 
Phone: (317) 278-5632

Detailed description of study

What will happen during the study?

This study will include a retrospective cohort for the creation of the AL measure and a prospective cohort for the validation of AL.  The patients for the prospective cohort will be recruited from OSUCCC, Indiana University Cancer Centers, and MetroHealth Systems. Further, data from the prospective cohort will be used to examine the relationship between AL, race, intrinsic breast cancer subtype, the tumor microenvironment and tumor mutations.

Eligibility of study

You may be eligible for this study if you meet the following criteria:

  • Conditions: Breast Cancer
  • Age: 18 years - 100 years
  • Gender: All

Inclusion criteria
•    Newly diagnosed yet untreated self-reported Non-Hispanic Black, Non-Hispanic White, Hispanic-Black, and Hispanic White patients with breast cancer, regardless of performance status ages ≥18 with clinical stages I-III breast cancer at diagnosis
•    Patients should have received one component of treatment (surgery, chemotherapy, or radiation therapy) at OSUCCC
•    No prior cancer diagnosis 
•    Diagnosed between 01/01/2012-12/31/2022
      

Exclusion criteria
•    Incarcerated individuals
•    Men
•    Known personal history of ductal carcinoma in situ (DCIS) or invasive breast cancer
•    Stage IV breast cancer
•    women identifying as American Indian, Alaskan Native, Asian, Native Hawaiian or Other Pacific Islander 
 

Updated on 10 Dec 2024. Study ID: CTO-2023C0120, 22506
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