Healthy Volunteers Needed for MRI Brain Imaging Study
Q
Qiuting Wen
Primary Investigator
Overview
Why is this study being done?
The purpose of this study is to image the brain using MRI. The brain naturally changes with age, but the causes behind these changes are largely unknown. We are developing new imaging technology to early detect small changes in the brain. The goal of our study is to increase our understanding of how the brain – specifically, its CSF flow dynamic – naturally changes with age. If proven successful, the new imaging tool can help early diagnose Alzheimer’s disease.
Who can take part in this study?
Healthy adults, ages 35 and older older, who do not have a history of neurodegenerative disorder, chemotherapy or radiation therapy, or previous brain surgery.
Description
What will happen during the study?
The study will be completed during a one-time visit at Goodman Hall (an IU building in downtown Indianapolis) which will take between 2.5 – 3.5 hours. During this study visit, you will be asked to complete the following:
· A health questionnaire
· A series of cognitive tests
· Have your blood pressure measured
· An MRI scan of your head
**While you are in the MRI, we will conduct an electrocardiogram and a (finger measure). In the ECG we will need to place some electrodes on your chest. This may require you to shave your chest/expose more of your chest area. To help with any discomfort that may arise with exposure of the chest, we recommend that you wear a bra without metal underwiring, so it can be worn in the MRI, that we can maneuver to place electrodes and limit exposure.)
Incentive/compensation
· For your involvement in the study, you will receive a $100 gift card as a token of appreciation.
Additional information
Study title: Map Neurofluid Dynamics in the Aging Brain
The study is being conducted by Dr. Qiuting Wen, PhD Assistant Professor at the Department of Radiology and Imaging Sciences, Indiana University School of Medicine. It is funded by the National Institute of Aging.
To learn more about Qiuting Wen and her research interests, please visit this link: https://medicine.iu.edu/faculty/6622/wen-qiuting
Eligibility
You may be eligible for this study if you meet the following criteria:
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Conditions:
Healthy, Hypertension
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Age: Between 35 Years - 100 Years
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Gender: All
Inclusion Criteria:
Fluent in and able to read English
8 years or more of formal education
Able to complete an MRI
Willing and able to provide written informed consent and answer questions about cognition and general health
Exclusion Criteria:
Previously diagnosed diabetes
Previously diagnosed neurodegenerative disorder
Any contraindications against MR (such as metal implants)
Previous brain surgery
Previous significant brain injury (loss of consciousness > 30 min)
History of chemotherapy or radiation therapy
History of cancer other than non-malignant skin lesions
Significant cerebrovascular disease or malformations
Women who are pregnant
Individuals who experience claustrophobia
Individuals with long fake nails or colored nail polish who are unwilling to remove
Updated on
29 Apr 2024.
Study ID: RADY-IIR-KEYAGING-AD, 19788
Pre-Screener
