Neonatal Caloric Absorption in Relation to Growth Outcomes and Nutrition

K
Katie Huff

Primary Investigator

Enrolling By Invitation
34 weeks - 100 years
All
Phase N/A
24 participants needed
2 Locations

Brief description of study

The goal of this study is to learn more about how babies in the NICU are able to take in and use the food they are getting. We want to follow babies during their stay in the NICU and measure their input and output, essentially, what’s in their diet and what’s in their poop and urine, and what the impact is on their growth.  
 
THIS STUDY IS ENROLLING BY INVITATION ONLY - Infants admitted to the Riley Hospital or Eskenazi Neonatal Intensive Care Unit (NICU) will be screened for eligibility with pre-determined inclusion and exclusion criteria For infants who are eligible, the parents of the patient will be approached and informed consent will be obtained by research personnel. If mother is also providing breast milk, consent will be obtained regarding obtaining breast milk samples. Recruitment may occur in person or over the phone with information given about study.

Detailed description of study

What will happen during the study?
  • Fecal and urine samples will be collected from infants in the NICU with no interaction by the research team as bedside nurses will collect samples. 
  • Based on eligibility criteria, some maternal breast milk and donor breast milk will be collected.
  • Infants at Riley NICUs may also be measured in the PEA POD if available.

Eligibility of study

You may be eligible for this study if you meet the following criteria:

  • Conditions: all, Riley
  • Age: 34 weeks - 100 years
  • Gender: All

Inclusion criteria:

  • Infants admitted to the Riley Hospital or Eskenazi Neonatal Intensive Care Unit (NICU) who are at least 34 weeks 0 days old, who are tolerating enteral feeds, are at least 96 hours old and have had 48 hours without need for IV fluids or parenteral fluids, largely stable as defined by not fitting the exclusion criteria, will be eligible for inclusion within the study.

Exclusion criteria:

  • Diagnosis or concern of cyanotic cardiovascular disease and/or heart failure
  • Diagnosis or concern for gastrointestinal diseases with malabsorption or liver dysfunction/disease
  • Diagnosis or concern of endocrine or metabolic disease or conditions
  • Diagnosis or concern for genetic disease, major congenital conditions, or chromosomal abnormalities
  • Current infection requiring antibiotic treatment in the last 48 hours

Updated on 21 Jan 2026. Study ID: PNEO-IIR-CARGO, 24197
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Interested in the study?

This study is accepting only persons who receive care at a certain clinic or doctor or who are part of an invited group. Questions about this study can be directed to the study team listed in the description or contact your doctor to see if you are eligible.

Accepting Referrals by Invitation Only