Older Adults Needed for Salt and Supplements Study
Austin T Robinson
Primary Investigator
Brief description of study
Why is this study being done?
Eating too much salt is common in the U.S. and increases the risk of high blood pressure and heart disease. Indiana University researchers are conducting a study to determine whether ketone supplements may help offset the negative health consequences of consuming too much salt.
Who can take part?
Adults (ages 50-85) who are generally healthy (have blood pressure no higher than 150/90 and do not have any metabolic, pulmonary, or cardiovascular diseases).
Must be willing to attend multiple study visits at Indiana University Bloomington campus and take study supplements as instructed.
Detailed description of study
What will happen during the study?
- During this study, you will complete one initial qualifying and information session that lasts about two hours (all study visits will take place at the Indiana University School of Public Health in Bloomington, IN).
- You will be asked to wear or bring athletic clothing to ALL study visits.
- This visit will be followed by three additional visits lasting approximately 3.5 to 4 hours each, during which you will undergo a blood draw, ultrasound imaging on your arm, leg, and torso, exercise on stationary cycle, and have blood pressure measures taken.
- Visits 2, 3, and 4 will be preceded by 10 days of placebo or supplement beverages and salt or placebo capsules, followed by at least a 14-day washout period before beginning the next supplemental period.
- Total study participation time is estimated to be 14-16 hours over the course of, at most, 4 months.
Incentive/compensation
- You will receive up to $800 for completing all of the study requirements.
- Additionally, you'll receive data on your diet, sleep, physical activity habits, body composition, and fitness.
- The study team can arrange transportation assistance for you via Uber, Lyft, or taxi, if needed.
Additional information
Study title: Ketone supplementation as a strategy to reduce the negative health effects of high dietary salt
- The study is being conducted by Dr. Austin Robinson and the Indiana University – Bloomington, Department of Kinesiology within the School of Public Health. It is funded by a grant from the National Institutes of Aging (NIA).
To learn more about Austin Robinson, Ph.D and his research interests, please visit this link:
https://publichealth.indiana.edu/research/faculty-directory/profile.html?user=ausrobin
Eligibility of study
You may be eligible for this study if you meet the following criteria:
- Conditions: Healthy
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Age: 50 years - 85 years
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Gender: All
Inclusion Criteria:
• Male and female participants ages 50-85
• Have a resting blood pressure no higher than 150/90 (stage 2 hypertension).
• Have a BMI below 35 Kg/m2 (otherwise healthy)
• Free from metabolic disease (diabetes or renal disease), pulmonary disorders (e.g., COPD, severe asthma, & cystic fibrosis), and cardiovascular disease (peripheral vascular, cardiac, or cerebrovascular).
• Do not have any precluding medical issues that prevent participants from exercising (i.e., cardiovascular issues, or muscle/joint issues including painful arthritis) or giving blood (e.g., blood thinners).
• Are not currently smoking, using smokeless tobacco, nor smoked within the past 12 months.
Exclusion Criteria:
• Have a resting blood pressure > 150/90.
• Have a BMI > 35 Kg/m2 or < 18 Kg/m2<br>• History of metabolic disease (diabetes or renal disease), pulmonary disorders (e.g., COPD, severe asthma, & cystic fibrosis), and cardiovascular disease (peripheral vascular, cardiac, or cerebrovascular).
• Medical issues that prevent safe exercise (i.e., cardiovascular issues, or muscle/joint issues including painful arthritis)
• Medical issues that prevent giving blood (e.g., blood thinners).
• Currently smoking, using smokeless tobacco, or vaping (within past 12 months).
• Currently pregnant
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