Indiana University Orthopaedic Sports Medicine Cohort Data Repository

Joint Damage and Symptoms After Sports Surgeries

B
Bryan Saltzman

Primary Investigator

Enrolling By Invitation
18 years - 30 years
All
Phase N/A
400 participants needed
1 Location

Brief description of study

The purpose of this study is to prospectively collect patient-reported outcome measures, biospecimens, and imaging on patients who undergo orthopaedic sports medicine surgeries. These data will be used to determine predictors and correlates of joint damage (i.e. cartilage, ligament or meniscal damage, as well as osteoarthritis and arthrofibrosis) on the day of surgery and patient symptoms (such as pain, stiffness, and function) on the day of surgery and at 6 weeks, 3 months, 6 months, and 1 year postoperatively.

THIS STUDY IS ENROLLING BY INVITATION ONLY - The study population will consist of patients undergoing hip, knee, or shoulder surgery. All study subjects are patients of two orthopaedic surgeons, who are study investigators. Initial screening will be performed by research personnel on the day of surgery. Potential study subjects will be approached and enrolled on the day of surgery in the pre-operative holding area in a private patient bay.

Detailed description of study

The study will occur at 5 time points: the day of surgery and at postoperative visits at 6 weeks, 3 months, 6 months, and 1 year.  (Table 5). The screening, consent form, enrollment form, initial joint-specific patient survey, collection of bio-specimens, and surgeon surveys will all be completed on the day of hip, knee, or shoulder surgery. 

At 6 weeks, 3 months, 6 months, and 1 year, the patient will be complete additional joint-specific surveys. 

The number of patients screened, enrolled, and who complete 6-week, 3-month, 6-month, and 1-year joint-specific surveys will be tracked throughout the course of the study 

Eligibility of study

You may be eligible for this study if you meet the following criteria:

  • Conditions: knee injury, hip injury, shoulder injury
  • Age: 18 years - 30 years
  • Gender: All

Inclusion Criteria: 

  • Scheduled for outpatient knee, hip, or shoulder surgery with member of sports medicine division in IU department of orthopaedic surgery
  • Ability to fill out electronic surveys and consents to complete electronic surveys at minimum 5 time points (day of surgery, 6 weeks after surgery, 3 months after surgery, 6 months after surgery, and one year after surgery)
  • Access to the internet and electronic devices to complete required surveys and communicate with research staff
  • Adequate physical and cognitive ability for completion of survey material, in the opinion of the principal investigator
  • Consents to allow bio-specimens to be collected on day of surgery

Exclusion Criteria: 

  • Prisoners or inmates (current) or has a conviction with pending completion of period of incarceration
  • Currently pregnant on day of surgery. This is defined as patient-reported current pregnancy or a positive pregnancy screen result on day of surgery.
  • Diagnosis of autoimmune arthritis
  • Use of oral corticosteroids or other systemic immunosuppressant medication on a regular basis
  • Diagnosis of a medical condition, as determined by the Principal Investigator, resulting in significant immune compromise
  • Active bacterial infection, any anatomic location
  • History of deep infection involving the planned surgical site. History of prior superficial infection such as cellulitis or suture abscess is allowable.  

This study investigates the outcomes of patients undergoing orthopaedic sports medicine surgeries, specifically focusing on joint damage and patient symptoms. The purpose of this study is to collect data such as patient-reported outcomes, biospecimens, and imaging from individuals having surgeries on their hips, knees, or shoulders. This information will help understand the predictors and correlates of joint issues like cartilage, ligament, or meniscal damage, as well as conditions such as osteoarthritis and arthrofibrosis, observed during surgery and at various times post-surgery.

Participants in the study will undergo several procedures. On the day of their surgery, they will complete an initial survey, provide biospecimens, and have imaging done. Follow-up surveys will be conducted at 6 weeks, 3 months, 6 months, and 1 year after surgery to track symptoms like pain, stiffness, and function. These procedures will help gather comprehensive data to study the long-term effects of the surgeries.

  • Who can participate: Participants must be scheduled for outpatient knee, hip, or shoulder surgery with the sports medicine division at IU's orthopaedic surgery department. They need internet access and must allow biospecimen collection on the surgery day.
  • Study details: Participants will provide biospecimens and complete surveys on the surgery day. Follow-up surveys will track recovery over time.
Updated on 06 Jul 2026. Study ID: ORTHO-IIR-25155, 25155
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Interested in the study?

This study is accepting only persons who receive care at a certain clinic or doctor or who are part of an invited group. Questions about this study can be directed to the study team listed in the description or contact your doctor to see if you are eligible.

Accepting Referrals by Invitation Only