Transient Elastography Database
Liver Fibrosis Study Using Sound Waves
Raj Vuppalanchi, MD
Primary Investigator
Brief description of study
The aim of this study is to maintain a prospective database of patients with known or suspected liver disease who undergo evaluation for liver fibrosis via transient elastography using FibroScan® and/or Hepatus® from Mindray. One scan will be done as standard of care and one will be done for research purposes. The database will be used to collect information for future research purposes relating to transient elastography.
Detailed description of study
Transient elastography using FibroScan® and Hepatus® will be performed at the Digestive and Liver Disease clinic and Indiana Clinical Research Center when ordered by the hepatologist caring for the patient. One scan will be for clinical care, the second scan will be for research purposes. The results of each scan will be entered into this database. For the purposes of this database, an informed consent will be obtained prior to the performance of the study and details regarding the patient demographics, indication, recent blood test results will be captured in addition to the test results. The data will then be stored in the electronic format at IU workstation computer that would require IU network password to login in. The database will be updated frequently based on the clinical volume. Duration of participation will be about 30 minutes.
Eligibility of study
You may be eligible for this study if you meet the following criteria:
- Conditions: Liver diseasae
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Age: 18 years or above
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Gender: All
Inclusion Criteria:
• referred for transient elastography by their respective physician
• ability to provide meaningful informed consent
• aged 18 years or older
• fasting for three hours
Exclusion Criteria:
• unable to provide informed consent
• aged less than 18 years
• fasting for less than three hours
This study investigates liver fibrosis in patients with known or suspected liver disease. Liver fibrosis is a condition where the liver becomes scarred due to long-term damage. The purpose of this study is to collect data using transient elastography, a method that uses sound waves to measure liver stiffness, which can indicate fibrosis.
During the study, participants will undergo two liver scans. One scan is part of their regular medical care, and the other is for research. Information from these scans, as well as patient details and recent blood test results, will be stored in a secure database for future research.
- Who can participate: Adults aged 18 or older who are referred for transient elastography by their physician and can provide informed consent are eligible. Participants must fast for three hours before the scan.
- Study details: Participants will undergo two liver scans using transient elastography at a clinic. One scan is for regular care, and the other is for research. Data from these scans will be stored securely.