Cardiac Vagal Effects of Gastric Electrical Stimulation and Vagal Nerve Action Potentials in Vagus nerve in Patients with Gastroparesis- Randomized Phase
T
Thomas Nowak, MD
Primary Investigator
Administratively Closed
18 years - 100 years
All
Phase
N/A
1 Location
Brief description of study
The purpose of this study is to assess if the Gastric Electric Stimulator (GES) device may influence the vagal output, which helps in the relief of the symptoms of gastroparesis, mainly nausea and vomiting.
Detailed description of study
The primary objective is to find if Gastric electrical stumulation (GES) may influence the flow in the vagus nerve when the signals are sent by the GES. Specifically this study will determine whether programming the GES device to produce optimal CNAPs results in better resolution of symptoms than empiric increases in stimulus current and frequency.
Eligibility of study
You may be eligible for this study if you meet the following criteria:
- Conditions: gastroparesis,1712391546
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Age: 18 years - 100 years
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Gender: All
Inclusion Criteria
Documented diagnosis of gastroparesis
Already has a GES device implanted
Severity and frequency of nausea and vomiting to be rated more than mild
Exclusion Criteria
Pregnancy
History of allergic reaction to EKG leads placement adhesives
Documented diagnosis of gastroparesis
Already has a GES device implanted
Severity and frequency of nausea and vomiting to be rated more than mild
Exclusion Criteria
Pregnancy
History of allergic reaction to EKG leads placement adhesives
Additional Information:
Updated on
26 Mar 2025.
Study ID: GI-IIR-VAGAL-NERVE, 1712391546
