Chronic Headache due to Mild Traumatic Brain Injury in Adults: Alterations of Brain Function Central Sensitization and Inflammatory Processes
K
Kelly Naugle
Primary Investigator
Not Recruiting
18 years - 65 years
All
Phase
N/A
1 Location
Brief description of study
The purpose of this study is to teach us more about why some people often experience headaches after having a mild traumatic brain injury. We need individuals who have NOT experienced a traumatic brain injury.
Detailed description of study
The purpose of this study is to teach us more about why some people often experience headaches after having a mild traumatic brain injury. We want to determine whether certain factors place individuals more at risk for experiencing headaches after a mild traumatic brain injury including pain sensitivity, how the body adapts to pain, levels of inflammation in our blood, and changes in brain structure and function.
Eligibility of study
You may be eligible for this study if you meet the following criteria:
- Conditions: headache,healthy,mild traumatic brain injury
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Age: 18 years - 65 years
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Gender: All
Inclusion Criteria
In good health
Have not had a traumatic brain injury
Do not experience chronic headaches
Exclusion Criteria
Chronic cardiovascular disease, metabolic disease, or renal disease
Neurological disease (e.g., Parkinson's Disease, multiple sclerosis, epilepsy)
Serious psychiatric conditions (schizophrenia, bipolar disorder) or hospitalization within the preceding year for psychiatric illness
Pre-existing chronic headache defined as having headache > 15 days/month over the past 3 months
Fractures of any kind
Chronic opioid use
Current use of narcotics
Uncontrolled hypertension (or receiving treatment for hypertension with BP of greater than 150/99)
Current involvement in litigation
No metallic foreign bodies in the brain or eye or cardiac pacemakers
Previous traumatic brain injury
Additional Information:In good health
Have not had a traumatic brain injury
Do not experience chronic headaches
Exclusion Criteria
Chronic cardiovascular disease, metabolic disease, or renal disease
Neurological disease (e.g., Parkinson's Disease, multiple sclerosis, epilepsy)
Serious psychiatric conditions (schizophrenia, bipolar disorder) or hospitalization within the preceding year for psychiatric illness
Pre-existing chronic headache defined as having headache > 15 days/month over the past 3 months
Fractures of any kind
Chronic opioid use
Current use of narcotics
Uncontrolled hypertension (or receiving treatment for hypertension with BP of greater than 150/99)
Current involvement in litigation
No metallic foreign bodies in the brain or eye or cardiac pacemakers
Previous traumatic brain injury
Participants will be compensated for their participation.
Updated on
01 Aug 2024.
Study ID: 1804170492
