Exploring How Brain Stimulation Affects Attention and Decision-Making

J
Joshua Brown

Primary Investigator

Exploring How Brain Stimulation Affects Attention and Decision-Making
Recruiting
18 years - 50 years
All
30 participants needed
1 Location

Brief description of study

This study is testing a new, non-invasive method of brain stimulation called temporal interference (TI). TI uses very small electrical currents non-invasively applied through the scalp to see whether deeper brain areas can be safely and effectively influenced. We are studying how TI affects brain activity, measured with MRI, and how it may change attention, decision-making, and responses to simple tasks. 

You may qualify for this study if you:

  • Are between the ages of 18 and 50
  • Weigh less than 440 pounds
  • Have at least a 6th grade education
  • Speak and read English
  • Can pass an MRI safety screening test

Detailed description of study

You will be asked to attend one study visit (~2–3 hours) at the IU School of Medicine in Bloomington, IN.

  • Electrodes will be placed on your scalp to deliver either active or sham TI stimulation while you undergo a brain imaging scan (MRI).
  • Your brain will be stimulated for different periods within that time while we measure brain activity and sensations (in some sub-studies, participants will also complete simple computer-based tasks involving attention or decision-making during scanning).
  • You will be asked to rate sensations and any mild discomfort during the stimulation.
  • You will receive $35/hour (approx. $70–$105 total per session). 

Eligibility of study

You may be eligible for this study if you meet the following criteria:

  • Conditions: Healthy
  • Age: 18 years - 50 years
  • Gender: All

Inclusion Criteria:
  • Ages 18–50
  • At least a 6th grade education
  • Able to read and speak English for all phases
Exclusion Criteria:
  • Psychotropic medications (e.g., for ADHD or other mental illness), cancer medications, epilepsy medications
  • History of seizure disorder, migraines, neurological syndromes, AIDS, head trauma, cognitive impairments, or psychosis symptoms
  • Metal implants in the head/scalp, cranial defects, pacemakers, tattoos on head/neck, permanent jewelry
  • Pregnancy (self-reported); IUD use unless model verified as MRI-safe
  • Weight > 440 lbs

Updated on 16 Nov 2025. Study ID: PSY-IIR-DEEP-BRAIN-STIM, 26941

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