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GLP-1 Medications and Food Experiences Study
R
Richard Mattes
Primary Investigator
Recruiting
18 years - 65 years
All
1 Location
Brief description of study
Have you recently started a GLP-1? You may qualify for a paid research study to help us learn how weight loss medications affect taste, appetite, and food choices.
Our study is exploring how certain weight-loss medications may affect how adults with obesity experience food. These medications, known as GLP-1 receptor agonists, are often used to support weight loss.
Study participation includes two in-person visits at Purdue University (West Lafayette, IN) and several short online activities over about two weeks.
Detailed description of study
What you can expect:
Visit 1: The first visit lasts about 1 hour and includes simple tests of taste, smell, and mouth sensations. You will also complete a short computer task that looks at attention to food-related images.
Online questionnaires and food diaries: After the first visit, you will complete a few short online questionnaires at home and record three one-day food diaries online (two weekdays and one weekend day).
Visit 2: The second in-person visit also lasts about 1 hour. During this visit, participants will rate their hunger and related feelings and view images of food while researchers measure natural body responses such as saliva and heart rate. Participants will also complete a computer-based task about food preferences.
Payment: You will receive $100 after completing the study.
Eligibility of study
You may be eligible for this study if you meet the following criteria:
- Conditions: Obese, Obesity, Overweight
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Age: 18 years - 65 years
-
Gender: All
Inclusion Criteria:
- Ages 18-65 years; any sex/gender.
- Body Mass Index (BMI) >30 kg/m².
- People who have been taking GLP-1 receptor agonists
for weight management for approximately 1 month
(±0.5 months).
Exclusion Criteria:
- Sensitivity or allergy to study solutions: Sucrose
(sweet solutions), sodium chloride (salty solutions), citric
acids (sour solutions), urea (bitter solutions), linoleic
acid (fatty stimuli), and milk. - Prior (ever) or planned (within one year) bariatric surgery.
Updated on
16 Feb 2026.
Study ID: IRB-2024-1407 (PURDUE)
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