Dominantly Inherited Alzheimer Network (DIAN)
M
Martin Farlow, MD
Primary Investigator
Enrolling By Invitation
18-100 years
All
Phase
N/A
2 Locations
Brief description of study
The overall purpose of this research is to understand the changes that occur in dominantly inherited Alzheimer disease.
Detailed description of study
The overall purpose of this research is to understand the changes that occur in dominantly inherited Alzheimer disease.
Eligibility of study
You may be eligible for this study if you meet the following criteria:
- Conditions: alzheimers disease
-
Age: Between 18 Years - 100 Years
-
Gender: All
Inclusion Criteria
Participant is cognitively normal or if demented does not require nursing home-level care.
Participant has identified two persons (minimum of one) who are not their full-blooded siblings who can serve as collateral sources for the study.
Participant is fluent in English at the 6th grade level or above
Exclusion Criteria
Pregnant women should not complete any in-person visit measures
Treatment with blood thinners, e.g. Warfarin
Coagulation abnormalities
Lumbar spinal surgery within the last 6 months prior to screening, or any lumbar spinal surgery that interferes with anatomy of the inter-vertebral spaces.
History of chronic or repeat CSF leakage following previous LP(s)
Active infectious process
Current or recent participation in research studies involving radioactive agents
Pacemakers
Electronically, magnetically, and mechanically activated implants
Metallic splinters in the eye
Ferromagnetic haemostatic clips in the central nervous system
Additional Information:Participant is cognitively normal or if demented does not require nursing home-level care.
Participant has identified two persons (minimum of one) who are not their full-blooded siblings who can serve as collateral sources for the study.
Participant is fluent in English at the 6th grade level or above
Exclusion Criteria
Pregnant women should not complete any in-person visit measures
Treatment with blood thinners, e.g. Warfarin
Coagulation abnormalities
Lumbar spinal surgery within the last 6 months prior to screening, or any lumbar spinal surgery that interferes with anatomy of the inter-vertebral spaces.
History of chronic or repeat CSF leakage following previous LP(s)
Active infectious process
Current or recent participation in research studies involving radioactive agents
Pacemakers
Electronically, magnetically, and mechanically activated implants
Metallic splinters in the eye
Ferromagnetic haemostatic clips in the central nervous system
Participants will be paid for their participation.
Updated on
01 Aug 2024.
Study ID: 1903023852
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