CARE Plus: An Innovative Community-based Addiction Reduction Program

J
Joanna Chambers, MD

Primary Investigator

Enrolling By Invitation
18 weeks or above
All
Phase N/A
2 Locations

Brief description of study

The purpose of this study is to understand how to provide better care to and improve outcomes in mothers and infants who are exposed to opioids during pregnancy in Marion County, Indiana. Care Plus will examine the various factors that may contribute to improved NAS outcomes and impact on the family unit.
 
THIS STUDY IS ENROLLING BY INVITATION ONLY - Participants will be recruited from Prenatal clinics within faculty practices and identified babies diagnosed with or at risk of Neonatal Abstinence Syndrome (NAS) at any Indianapolis hospital.

Detailed description of study

This study will pilot 2 groups: 1) Non-intervention group – will not receive attachment therapy or COS-P sessions, and 2) Intervention group – will receive attachment therapy and COS-P sessions.

Eligibility of study

You may be eligible for this study if you meet the following criteria:

  • Conditions: Neonatal abstinence syndrome, NAS, Pregnancy, Pregnant
  • Age: 18 weeks or above
  • Gender: All

List inclusion criteria - eligibility criteria for subjects. 
•    Infant admitted to any Indianapolis hospital nursery or pregnant mother with OUD who will deliver at any Indianapolis hospital nursery

•    Mother’s age ≥18 years old

•    Mother on MAT during pregnancy or Infant diagnosis of NAS

•    Mother is primary caregiver of infant
 

List exclusion criteria (any criteria which would exclude otherwise acceptable subjects). 
•    Mother with Intellectual deficit (IQ less than 70)

•    Mother with Active psychotic Disorder (i.e. Schizophrenia or Schizoaffective Disorder)

•    Unwillingness to provide informed consent

 

Exclusion Criteria for Infant Developmental Outcomes Testing

•    Chromosomal and congenital abnormalities

•    Born <37 + 0 weeks gestational age

 

Updated on 16 Dec 2025. Study ID: PCTR-IIR-CAREPLUS, 1805278102
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Interested in the study?

This study is accepting only persons who receive care at a certain clinic or doctor or who are part of an invited group. Questions about this study can be directed to the study team listed in the description or contact your doctor to see if you are eligible.

Accepting Referrals by Invitation Only