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Found 742 results
A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
How Do You Move? Participants Needed for MRI Study
Alexandra Moussa-Tooks
Why is this study being done?The purpose of this study is to understand how movement and sensory characteristics (e.g., posture, walking, hand and arm based reaching) present in psychotic disorders over time. Who can take part?We are looking for individuals, ages 18-55, who have been diagnosed with Schizophrenia, Schizoaffective Disorder, Schizophreniform …
Denosumab for Type 1 Diabetes
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Carmella Evans-Molina, MD
Researchers at City of Hope (California), University of Alabama at Birmingham, and Indiana University are studying a medication called denosumab as a potential treatment for people with type 1 diabetes. Denosumab, also known as Prolia, is a drug that has been approved by the Food and Drug Administration for bone …
Lend Your Ears (and Brains) For Hearing Research!
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Michael Heinz
Why is this study being done?The purpose of this study is to better understand how our ears and brains help us perceive the world around us. In particular, we are interested in understanding how our senses allow us to have conversations in complex environments such as crowded restaurants and busy …
Prospective Study on Radiation Induced Cardiotoxicity Assessed By PET-CT for Locally Advanced Non-Small Cell Lung Cancer
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Tim Lautenschlaeger
There has been evidence that patients being treated with chemoradiation for Non-Small Cell Lung Cancer (NSCLC) have experienced cardiac toxicities (heart damage). This study is exploring if testing patients hearts that have been diagnosed with NSCLC before and after treatment can help investigators decrease heart damage for patients in the …
Older Adults Needed for Salt and Supplements Study
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Austin T Robinson
Why is this study being done?Eating too much salt is common in the U.S. and increases the risk of high blood pressure and heart disease. Indiana University researchers are conducting a study to determine whether ketone supplements may help offset the negative health consequences of consuming too much salt.Who can …
Exploring Treatment Options After Lung Cancer Surgery
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Vijaya L. Kakani, MD
Do you have non-small cell lung cancer (NSCLC) but the cancer was not fully removed by surgery? You may qualify for a study exploring treatment options for NSCLC.This research study is testing whether adding a medication called sacituzumab tirumotecan to pembrolizumab after surgery may help prevent non-small cell lung cancer …
A Phase II Study of Pembrolizumab, Carboplatin, Paclitaxel, and Radiationfor the Treatment of Early-Stage Anal Cancer
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Anita Turk, MD
Primary Objective:1. To determine the clinical complete response rate (cCR) assessed following weekly carboplatin and paclitaxel in combination with pembrolizumab and radiation for the treatment of early-stage anal cancer. Secondary Objectives:1. To assess the safety and tolerability of weekly carboplatin and paclitaxel in combination with pembrolizumab and radiation for the treatment …
Women Needed for Early Detection of Sjögren’s Disease Study
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Thankam Thyvalikakath
This study is looking at finding biomarkers in blood and saliva samples that will help detect the symptoms of Sjrogrens disease earlier than current diagnosis time. Sjögren's disease is an autoimmune disease that affects the mucous membranes and moisture-secreting glands of your eyes and mouth, resulting in decreased tears and …
A Phase 1, Open Label, Multiple Dose, Dose Escalation and Expansion Study to Investigate the Safety, Tolerability, Pharmacokinetics and Antitumor Activity of the PTK7-Targeted Antibody-drug Conjugate DAY301 in Patients with Locally Advanced or Metastatic Solid Tumors
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Greg Durm, MD
This is a Phase 1a/1b, open-label, dose escalation and expansion study to evaluate the safety and anti-tumor activity of DAY301, a PTK7-directed antibody-drug conjugate in patients with advanced or metastatic solid tumors. Interested in participating? For more information about this research study or other cancer-related clinical trials at IU Simon Comprehensive …
A Phase 3, Open-label, Multicenter, Randomized Trial of TrastuzumabDeruxtecan with Bevacizumab Versus Bevacizumab Monotherapy asFirst-line Maintenance Therapy in HER2-Expressing Ovarian Cancer.
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Jessica Parker
This clinical trial is designed to evaluate the efficacy and safety of T-DXd in combination with bevacizumab versus bevacizumab monotherapy as first-line maintenance therapy, in participants with human epidermal growth factor 2 (HER2)-expressing (immunohistochemistry [IHC] 3+/2+/1+) advanced high-grade epithelial ovarian cancer.Interested in participating? For more information about this research study …
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