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A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
Forager-2: A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Efficacy and Safety of Vepugratinib Combined with Enfortumab Vedotin and Pembrolizumab in Adults with Untreated Locally Advanced or Metastatic Urothelial Carcinoma with an Fgfr3 Genetic Alteration.
T
Tareq Salous
This phase II clinical trial tests how well pembrolizumab plus enfortumab vedotin prior to and after radical nephroureterectomy works in treating patients with high-risk upper tract urothelial cancer. Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune system attack the cancer, and may interfere with the ability …
Discover a New Path to Hope: Join a Study That’s Working to Improve Care for Depression
S
Steve Strakowski
Take the First Step Toward Feeling Better—Join Our Depression Study Today!Living with depression can feel heavy, even on your best days. If you’re looking for new options—or simply wondering what else might help—you’re not alone. This research study is exploring a possible new treatment for major depression, and you may be …
Vape Study: Help us Understand Nicotine Dependence with Brain Stimulation
J
Joshua Brown
Do you use nicotine-based vapes? Our study is testing the effects of brain stimulation on nicotine use and craving. Temporal interference (TI) delivers very mild electrical currents to the scalp that reach deeper brain regions linked to addiction, without surgery. You may qualify to be in this study if you:Are between the …
Exploring How Brain Stimulation Affects Attention and Decision-Making
J
Joshua Brown
This study is testing a new, non-invasive method of brain stimulation called temporal interference (TI). TI uses very small electrical currents non-invasively applied through the scalp to see whether deeper brain areas can be safely and effectively influenced. We are studying how TI affects brain activity, measured with MRI, and …
A Randomized, Active-Controlled, Double-Blind, Multicenter, Phase 3 Clinical Study of Ivonescimab in Combination with Folfox Versus Bevacizumab in Combination with Folfox for the First-Line Treatment of Metastatic Colorectal Cancer
A
Anita Turk, MD
Primary ObjectiveTo compare the progression-free survival (PFS) as assessed by blinded Independent. Radiological Review Committee (IRRC) based on Response Evaluation Criteria in. Solid Tumors (RECIST) v1.1, of ivonescimab in combination with modified 5-FU, oxaliplatin, and leucovorin (mFOLFOX6) to bevacizumab in combination with mFOLFOX6.Secondary ObjectivesTo compare the overall survival (OS) of …
Docetaxel Addition In Metastatic Castrate-Sensitive Prostate Cancer (Aspire)
N
Nabil Adra, MD
This phase III trial compares the effect of adding docetaxel to hormonal therapy and apalutamide versus hormonal therapy and apalutamide alone in treating patients with prostate cancer that has spread from where it first started (primary site) to other places in the body (metastatic). Docetaxel is in a class of …
A Phase 2, Multi-Center, Randomized, Double-Blind, Placebo-Controlled, Dose-Ranging Study to Evaluate the Safety and Efficacy of Aga2115 in Adults With Type I, Iii, or Iv Osteogenesis Imperfecta (Oi)
E
Erik Imel, MD
This study will determine the effect of treatment of AGA2115 in adults with Type I, III, or IV osteogenesis imperfecta versus placebo
A Randomized, Open-Label Study Evaluating The Efficacy And Safety Of Cemacabtagene Ansegedleucel In Participants With Minimal Residual Disease After Response To First Line Therapy For Large B-Cell Lymphoma (Alpha3)
V
Varun Mittal
This is a randomized, open-label study in adult patients who have completed standard first line therapy for large B-cell lymphoma (LBCL) and achieved a complete response or partial response suitable for observation, but who have minimal residual disease (MRD) as detected by the Foresight CLARITY™ Investigational Use Only (IUO) MRD …
Randomized, Open-Label Study of the Bria-Imt Regimen and Check Point Inhibitor Vs Physician S Choice in Advanced Metastatic Breast Cancer (Bria-Abc)
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Tarah Ballinger, MD
The purpose of this study is to evaluate the effect of the Bria-IMT regimen in combination with Check Point Inhibitor (CPI) on overall survival (OS) compared to treatment of physician’s choice (TPC) chemotherapy in patients with metastatic breast cancer with no approved alternative therapies available as per the Inclusion criter …
A Phase 2, Open-Label, Single-Arm, Multicenter Study to Evaluate the Efficacy of Cemsidomide + Dexamethasone in Subjects With Relapsed/Refractory Multiple Myeloma
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Attaya Suvannasankha, MD
The purpose of this Phase 2 study is to assess the antimyeloma activity and further characterize the safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of cemsidomide in combination with dexamethasone in subjects with relapsed/refractory multiple myeloma (r/r MM).Interested in participating? For more information about this research study or other cancer-related …
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