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Found 759 All Conditions trials

A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Study on Therapy Reduction in Early-stage Triple-negative Breast Cancer

N
Nawal Kassem
18 years - 100 years
All genders
Phase 3
This study investigates the effects of continuing pembrolizumab treatment versus observation in patients with early-stage triple-negative breast cancer (TNBC) who have achieved a pathologic complete response (pCR) after receiving chemotherapy and pembrolizumab before surgery. Triple-negative breast cancer is a type of cancer that lacks three common receptors known to fuel …
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Analysis of Senescent Markers in Periodontal and Periimplant Tissue

C
Chandni Batra
18 years - 100 years
All genders
The aim of our study is 1) to analyze the level of senescence markers in periodontally healthy and diseased gingival tissue;2) to analyze the level of senescence markers in periodontal and periimplant diseased gingival tissues and reveal the association between cellular senescence or ageing on progression of periodontal disease and …
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Clinical factors affecting renal recovery in pediatric critical illness.

D
Daniel Cater
28 days - 17 years
All genders
This is an observational prospective study and a retrospective study. For the prospective study, the clinical data and blood sample will be collected in accordance with standard procedure currently used in patient care at our institutions. For the retrospective study, patients requiring acute dialysis in the pediatric ICU and CVICU …
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Pilot Pharmacokinetic Study of VAL-413 (Orotecan) in Patients with Recurrent Pediatric Solid Tumors

K
Kyle William Jackson
1 years - 30 years
All genders
Phase 2
What is the purpose of this study?To establish the recommended phase II dose of a flavored preparation of orally administered irinotecan (VAL-413) when given in combination with temozolomide for five consecutive days. To characterize and compare the pharmacokinetic profiles of VAL-413 and conventional irinotecan given orally To evaluate the palatability …
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Household Material Hardship

S
Scott Coven
21 years or below
All genders
This proposal will expand on our current work with the SRC/IRB approved project (IRB: #15991 Assessing Household Material Hardship in Children with Central Nervous System (CNS) Tumors). This new population can serve as a comparison, with children admitted to the hospital for infectious diseases and requiring long hospital stays and/or …
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CHAP Maternal Follow-Up Study

D
David Haas, MD
18 years - 100 years
Female
This protocol describes the epidemiology, international controversy and current state of knowledge regarding long-term maternal outcomes among women with mild CHTN who received antihypertensive therapy in pregnancy or who had preeclampsia. This document is considered a written agreement between participating investigators and their corresponding centers. Changes to the protocol during …
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RDCRN PIDTC

M
Miriam Kim, DO
17 years or below
All genders
In this prospective and longitudinal natural history study, the aim is to identify variables that affect long-term outcomes following potentially life-saving Definitive Therapy (DT), which includes either 1) allogeneic hematopoietic cell transplant (HCT), or 2) autologous gene therapy (GT).
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Immunoassay of Gingival and Peri-implant Crevicular Fluid

A
Alexandru Movila, PhD
18 years - 100 years
All genders
The goal of this study is to use a new immune monitoring (test and define properties of the patient’s cells). This information will help work towards :in vitro panel kit, that analyzes properties like 65 cytokines, chemokines, growth factors/regulators, and soluble receptors simultaneously within 1) the GCF(gingival crevicular fluid) of …
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Long-FRI

R
Roman Natoli, MD
18 years - 85 years
All genders
The overall aim of this proposal is to identify a biomarker diagnostic strategy that can be implemented in patients sustaining fractures at high-risk for infection. This proposal will address the hypothesis that there is a biomarker signature that will be able to discriminate between patients who develop FRI compared to …
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Olfactory Neurons Study

K
Kathy Newell
100 years or below
Accepts healthy volunteer
All genders
We propose to study cells obtained from the upper nose in patients with clinically diagnosed Alzheimer Disease or related dementia, and amyotrophic lateral sclerosis. There is evidence that cells from the nose may show changes associated to these neurological illnesses. The study of cells from normal subjects is necessary for …
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