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Found 756 All Conditions trials

A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Adenovirus-specific Cytotoxic T-lymphocytes for Refractory Adenovirus Infection

S
Scott Goebel, MD
1 month - 79 years
All genders
Phase 2
Interventional
What is the purpose of this study?Related donor Adenovirus (ADV) specific cytotoxic T cells (CTLs) manufactured with theyi CliniMACS Prodigy Cytokine Capture System will be administered intravenously in inhildren, adolescents and young adults with refractory ADV infection post Allogeneic Hematopoietic Stem Cell Transplantation (AlloHSCT), with primary immunodeficiencies (PID) ord organ …
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Virus Specific Cytotoxic T-Lymphocytes (CTLs) for Refractory Cytomegalovirus (CMV)

S
Scott Goebel, MD
1 month - 30 years
All genders
Phase 2
Interventional
What is the purpose of this study?CMV cytotoxic T cells (CTLs) manufactured with the Miltenyi CliniMACS Prodigy Cytokine Capture System will be administered in children, adolescents and young adults (CAYA) with refractory cytomegalovirus (CMV) infection post Allogeneic Hematopoietic Stem Cell Transplantation (AlloHSCT), with primary immunodeficiencies (PID) or post solid organ …
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A Phase 2 Trial of Chemotherapy followed by Response-Based Whole Ventricular & Spinal Canal Irradiation (WVSCI) for Patients with Localized Non-Germinomatous Central Nervous System Germ Cell Tumor.

S
Sandeep Batra, MD
3 years - 30 years
All genders
Phase 2
Interventional
What is the purpose of this study?This phase II trial studies the best approach to combine chemotherapy and radiation therapy (RT) based on the patient's response to induction chemotherapy in patients withgerminomatous germ cell tumors (NGGCT) that have not spread to other parts of the brainbody (localized). This study has …
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Intensive Glycemic Targets in Overweight and Obese Women With Gestational Diabetes (iGDM)

C
Christina M. Scifres, MD
18 years - 45 years
Female
Interventional
This is a multicenter randomized clinical trial of 828 overweight and obese individuals with gestational diabetes designed to compare standard to intensive glycemic targets.
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Biomarker of Diabetic Retinopathy

A
Ashay D. Bhatwadekar, PhD, MPHARM
18 years or above
All genders
Observational
What is the purpose of this study?Diabetic retinopathy is characterized by damage to retinal blood vessels. At present, there is no diagnostic marker reflecting retinal vascular health. By studying RNA content (genetic material that makes proteins) in highly specialized cells in circulating blood resembling blood vessels, we will discover biomarker …
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ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD)

D
David Clark
18 years or above
Accepts healthy volunteer
All genders
ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD) represents thezed integration of ARTFL (U54 NS092089; funded through 2019) and LEFFTDS (U01 AG045390; funded through 2019) as a single North American research consortium to study FTLD2019 and beyond.
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Oral Ifetroban in Subjects With Duchenne Muscular Dystrophy (DMD)

J
John Parent, MD
7 years or above
Male
Phase 2
Interventional
What is the purpose of this study?Duchenne muscular dystrophy (DMD) is a devastating X-linked disease which leads to loss ofbulation between ages 7 and 13, respiratory failure and cardiomyopathy (CM) at any age, an dvitably premature death of affected young men in their late twenties. DMD is the mostgenetic disorder …
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A Study to Assess the Long-Term Safety and Efficacy of Eplontersen (Formerly Known as ION-682884, IONIS-TTR-LRx and AKCEA-TTR-LRx) in Patients With Hereditary Transthyretin-Mediated Amyloid Polyneuropathy

N
Noel Dasgupta
18 years or above
All genders
Phase 3
Interventional
The purpose of this study is to evaluate the safety and tolerability of extended dosing withwith hereditary transthyretin-mediated amyloid polyneuropathy (hATTR-PN).
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Registry of Patients With Brain Tumors Treated With STaRT (GammaTiles)

M
Mitesh Shah, MD
100 years or below
All genders
Observational
What is the purpose of this study?The objectives of this registry study are to evaluate real-world clinical outcomes andd outcomes that measure the effectiveness and safety of STaRT.THIS STUDY IS ENROLLING BY INVITATION ONLY - Consistent with most oncology trials, patients are not actively “recruited,” but are screened by their …
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Prevalence and Predictors of Hepatic Steatosis in Persons Living With HIV

N
Naga Chalasani, MD
18 years - 80 years
All genders
Observational
Nonalcoholic fatty liver disease (NAFLD) is a spectrum of liver conditions associated withumulation that ranges from benign, non-progressive liver fat accumulation to severever injury, cirrhosis, and liver failure. NAFLD is the most common liver disease in USdults and the second leading cause for liver transplantation in the US. The natural …
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