A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
Objectives: To 1) determine performance characteristics of ultrasound (US), magnetic resonance imaging (MRI) and genetic testing (GT) in the prenatal diagnosis of aqueductal stenosis; 2) determine the gestational age that the diagnosis can be accurately made, and 3) to determine pediatric outcomes at 2 years in a contemporarily managed cohort …
This study investigates a device designed to monitor pressure inside the skull of neonates and infants who are at risk of developing hydrocephalus, which is a condition where there is a build-up of fluid and pressure in the brain. The device measures changes in the anterior fontanelle, also known as …
What is this study about?Coarctation of the aorta (CoA) tissues contain distinctive cell populations, and comprehensive analysis of these cells will provide understanding of cell abnormalities that are driving CoA. We want to define these types of cells that are abnormally located in the diseased aortic tissues of neonates with …
Measure the levels of key metabolites in maternal blood during pregnancies where the children developed ASD or were typically-developing (TD). If successful, this study will result in a diagnostic test for risk of having a child with ASD, and suggest treatments during pregnancy such as folate, vitamin B12, and carnitine …
What is the purpose of this study?This is a multicenter, prospective, observational Phase 4 study in the United States. The study is designed to collect both medical history and prospective data on Duchenne muscular dystrophy (DMD) treatment outcomes in participants receiving delandistrogene moxeparvovec as part of clinical care, compared to …
Placental chorangioma is a rare pregnancy complication but with significant maternal and fetal consequences. Chorangioma is a benign tumor of the placenta. As it grows, it can cause pregnancy complications. Little is known about the natural history of placental chorangioma or its response to in-utero intervention. The aim of this …
This study investigates whether adding chemotherapy to ovarian function suppression and hormone therapy improves breast cancer-free survival in premenopausal women. The focus is on those with early-stage breast cancer that is estrogen receptor-positive and HER2-negative. The study will compare outcomes between those receiving chemotherapy in addition to hormone treatments and …
This study investigates the effectiveness of using a combination of investigational medications, nivolumab and ipilimumab, compared to nivolumab alone in treating patients with recurrent endometrial cancer. Endometrial cancer is a type of cancer that begins in the lining of the uterus. This study focuses on a specific type of endometrial …
WHY IS THIS STUDY BEING DONE?The main reason for this research study is to understand what happens with patients who are treated for giant omphaloceles (GO) using a non-invasive staged closure technique that uses a hydrocolloid (Duoderm CGF) silo. Omphaloceles are a rare (birth) defect where infants are born with …
What is the purpose of this study?The brain is protected from any toxic or inflammatory molecule by the blood-brain barrier (BBB). This physical barrier is located at the level of the blood vessel walls. Because of these barrier properties, the blood vessels are also impermeable to the passage of therapeutic …
